Acute Trauma Brain Injury, Intacranial Hypertension, Subarachnoidal Hemorrhage
Conditions
Brief summary
During the first week after an acute cerebral injury, neurologic clinical exam is often irrelevant, limited by sedation use or spontaneous consciousness disorders. Hence, neurological monitoring of brain oxygen consumption, metabolic disorders, electrical activity is used to follow and prevent delayed cerebral injuries. Among those instruments, numerous are often described: intra cranial pressure monitoring, brain tissue oxygen pressure monitoring, scalp electroencephalography, continuous electroencephalography and Near infrared Red Spectroscopy (NIRS). Even if the value of some of those technologies are well known, many remain part of a research domain. Here we will not only try to study the correlation between different cerebral autoregulation's index described in the scientific literature but also will we try to identify and describe EEG and cardiorespiratory changes during the first week following brain injury. The objective of this study is to investigate the pathophysiology of acute brain injury and explore potent biomarkers of multimodal monitoring during the first week following acute brain injury.
Interventions
OTHERStudy the evolution and correlation between cerebral autoregulation index
Objective n°1: Study the correlation between autoregulation index: The investigators will look for a correlation between several auroregulation index such as the PRx, ORx and Cox. Objective n°2: Evaluation and detection of EEG prognostic patterns: The investigators will look for quantitaive EEG changes during the early phase of acute brain injuries.
Sponsors
Hospices Civils de Lyon
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* \- Patients hospitalized in neurologic critical care in Wertheimer Hospital, Bron * Monitored with the CNS MOBERG® monitoring system
Exclusion criteria
* \- Refusal to participate * Patients under legal protection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Correlation between ORx and PRx | Multimodal neuro monitoring is used from 1 to 15 days after the acute brain injury. |
Countries
France
Contacts
Primary ContactDr Baptiste Balança
Outcome results
None listed