Comparing Montiroing Cardiac Index by Transpulmonary Thermodilution and Transesophageal Echocardiography During Liver Transplantation

Is Cardiac Index, Assessed by Transpulmonary Thermodilution, Reliable During Liver Transplantation Compared to Transesophageal Echocardiography : a Monocentric Cohort

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06899867

Enrollment

Registered

2025-03-28

Start date

2023-11-27

Completion date

2025-11-01

Last updated

2025-03-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver Transplantation

Brief summary

Liver transplantation poses challenges due to hemodynamic changes throughout different surgical phases. Monitoring devices are essential for therapeutic adjustments. Transpulmonary thermodilution and transesophageal echocardiography are commonly used, but thermodilution may have limitations depending on the surgery. This study aims to compare cardiac index variations between thermodilution and transesophageal echocardiography during liver transplantation. Patients undergo monitoring with both techniques. Measurements are recorded and reported at multiple time points.

Interventions

OTHERMeasure of cardiac index with thermodilution and transesophageal echocardiography

At 4 times of surgery, end-expiratory occlusion (EEO) test and measure of cardiac index before and after test with ETO and thermodilution

OTHERSurgical anastomosis echography

Visualisation of surgical anastomosis through transesophageal echocardiography : stenosis, doppler velocity, collar diameter

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

* liver transplantation * adults

Exclusion criteria

* \- Oesophageal varice ligation \< 14 days * Mediastinal radiotherapy * Femoral bypass * Severe lower extremity artery disease

Design outcomes

Primary

Measure	Time frame
Cardiac index variation measured by thermodilution compared with transesophageal echography	At 4 times of surgery: after starting anesthesia, anhepatic phase, reperfusion and surgical anastomosis of biliary ducts. Data reported : - Cardiac Index before and after end-expiratory test. - Transoesophageal echography measurement of cardiac function

Countries

France

Contacts

Primary ContactPr Alice Blet

alice.blet@chu-lyon.fr371239

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026