Pain Management
Conditions
Brief summary
to investigate the postoperative analgesic effect of dexmedetomidine addition with different doses as an adjuvant to bupivacaine to Erector spinae plane block after renal surgeries.
Interventions
DRUGDexmedetomidine
different doses of dexmedetomidine added to bupivacaine in erector spinae plane block
Sponsors
Assiut University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Age between 18 and 70 years. * Both sexes, males and females. * Patients with the American Society of Anesthesiologists (ASA) physical status I/II. * Body mass index (BMI) of 18-35 kg/m2 * Patients scheduled for elective Renal or Percutaneous Nephrolithotomy.
Exclusion criteria
* Patients under 18 years. * Patient refusal of nerve block. * Infection at the site of injection. * Coagulopathy. * Allergy to used medications. * Psychiatric disorder or chronic pain syndromes. * Chronic opioid use or substance abuse. * Quadriplegic patients.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| postoperative analgesic duration | 24 hours | postoperative analgesic duration with each dose |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pain score | 24 hours | severity of pain using visual analogue pain score |
| side effects | 24 hours | as hemodynamic effect as (hypotension, bradycardia), nausea and vomiting. |
| dynamic pain score | 24 hours | Dynamic visual analogue pain score (pain with cough, deep breath, and movement) |
Countries
Egypt
Outcome results
None listed