Drinking Behavior
Conditions
Brief summary
To assess the effectiveness and safety of probiotic strain BC179 in reducing alcohol absorption in the gut, thereby lowering health risks.
Interventions
DIETARY_SUPPLEMENTProbiotic group
The experimental phase of this study lasted for 60 days.
DIETARY_SUPPLEMENTPlacebo group
The experimental phase of this study lasted for 60 days.
Sponsors
Wecare Probiotics Co., Ltd.
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Inclusion Criteria: 1. Participants must be aged between 18 and 65 years. 2. They should have a documented history of long-term alcohol consumption, defined as consuming at least 20 grams of ethanol per day for at least one year. This is calculated using the formula: volume (mL) × alcohol content (%) × 0.8. 3. They must provide written informed consent and be willing to comply with the study procedures. *
Exclusion criteria
1. History of chronic liver, gastrointestinal, or systemic metabolic disorders. 2. Use of products with similar functions to the investigational formulation within the past two weeks. 3. Use of antibiotics, laxatives, or dietary supplements within the past four weeks. 4. Documented history of hypertension or diabetes. 5. Severe allergies or immune deficiencies. 6. Pregnancy, lactation, or planning pregnancy without effective contraception during the study period.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Effects of BC179 on alcohol metabolism | 60 days | The impact of BC179 on alcohol metabolism is assessed by monitoring blood alcohol concentration (BAC) and related enzyme activities, such as alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH). |
Countries
China
Outcome results
None listed