Affect (Mental Function), Anxiety, Sleep, Stress
Conditions
Keywords
fibre, depression, anxiety, stress, optimism, sleep, gut health
Brief summary
This feasibility study will explore whether adding an extra 10 grams of fibre to participants' daily diet for two weeks would improve their mental health and wellbeing.
Detailed description
The current pre-post single-arm feasibility trial will investigate whether increasing daily fibre intake by 10 grams for two weeks enhance depression, anxiety, stress, sleep quality, gut health, and optimism in 18-40 year-old young adults. Participants will be provided a list of high fibre food items. Outcome measures will be acquired before and after 2-weeks . These will include cognitive measures of measures of depression, anxiety, and stress symptomatology; sleep; gastrointestinal symptomatology; optimism.
Interventions
OTHERFibre arm
Increasing daily fibre intake by 10 grams
Sponsors
University of Reading
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* Aging between 18-40 years old * Having normal vision and hearing * Having a body mass index between 18.5 and 30 * Not following a high fibre diet \>20g fibre/day as assessed by using the FiberScreen
Exclusion criteria
* Smoking * Having food allergies * Following restrictive and/or unbalanced diets * Changing dietary intake majorly in past month * Being diagnosed with any psychiatric or neurologic conditions * Being diagnosed with any cardiometabolic diseases, or hypertension or thrombosis related disorders or suffer from thyroid disease * Currently taking anticoagulants, antiplatelet medication, antidepressants, proton-pump inhibitors * Currently consuming prebiotic or probiotic supplements or laxatives * Continuous antibiotic use for \> 3 days within 1 month prior to enrolment * Continuous use of weight-loss drug for \> 1 month before screening * Having a significant gastrointestinal (GI) condition
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Generalized Anxiety Disorder 7 scale scores | From baseline (pre intervention) to week 2 (post intervention) | A validated self-report measure of anxiety |
| Patient Health Questionaire-8 scores | From baseline (pre intervention) to week 2 (post intervention) | A validated self-report measure of depression |
| Perceived Stress Scale scores | From baseline (pre intervention) to week 2 (post intervention) | A validated self-report measure of stress |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pittsburgh Sleep Quality Index scores | From baseline (pre intervention) to week 2 (post intervention) | A validated self-report measure of sleep quality |
| Gastrointestinal Symptom Rating Scale Scores | From baseline (pre intervention) to week 2 (post intervention) | A validated self-report measure of gastrointestinal symptoms that includes 15-items (combined into five symptom clusters depicting Reflux, Abdominal pain, Indigestion, Diarrhoea and Constipation) |
| Revised Life Orientation Test Scores | From baseline (pre intervention) to week 2 (post intervention) | A validated self-report measure of one's dispositional level of optimism |
Other
| Measure | Time frame | Description |
|---|---|---|
| EPIC Norfolk Food Frequency Questionnaire (FFQ) | Baseline (pre intervention) only | The FFQ is a validated tool for gauging the average habitual dietary intake of micro and macronutrients of an individual in the UK. Data will be processed using the FETA software. |
| FiberScreen Scores | From baseline (pre intervention) to week 2 (post intervention) | A questionnaire that assesses fibre intake. It will be used to screen participants. Individuals who adhere to a high fibre diet (\>20g fibre/day) will be excluded from the study. |
Countries
United Kingdom
Outcome results
None listed