The Association Mechanism Between the Microbiome and the Development of Community Pneumonia Was Studied Based on the Analysis of Pulmonary Microbiota - Host Interaction Network

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06896019

Enrollment

Registered

2025-03-26

Start date

2023-06-01

Completion date

2025-12-12

Last updated

2025-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Community Pneumonia

Brief summary

1. The difference of lung flora between the healthy group and the CAP group was compared, and the core flora involved in the development of CAP was identified. 2. To predict the metabolites associated with CAP. 3. Identification of genes related to immune response in CAP. 4. Construct the pulmonary microbiota - host interaction network with metabolites as the link.

Interventions

DIAGNOSTIC_TESTCommunity Pneumonia

The BALF of CAP patients

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* According to the CAP clinical diagnostic criteria in the Guidelines for the Diagnosis and Treatment of Community-Acquired Pneumonia in Adults in China (2016 edition), cases eligible for community-acquired pneumonia were included and screened.

Exclusion criteria

* Alveolar lavage fluid samples without electronic bronchoscopy were excluded for mNGS etiological examination of the case.

Design outcomes

Primary

Measure	Time frame	Description
Community Pneumonia	1 weeks	mNGS

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026