Deep Parasternal Intercostal Plane Block

Deep Parasternal Intercostal Plane Block : Effect on the Quality of Postoperative Recovery After Cardiac Surgery

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06895876

Acronym

DPIP

Enrollment

128

Registered

2025-03-26

Start date

2022-08-10

Completion date

2025-06-15

Last updated

2026-05-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nerve Block

Keywords

Transversus thoracic muscle plane block, Cardiac surgery, Postoperative analgesia, Quality of recovery, QoR-15

Brief summary

Cardiac surgery is a source of severe post operative pain witch can cause major respiratory complications due to non optimal post operative rehabilitation. Multimodal analgesia provides acceptable pain control , but does not seem sufficient during coughing or mobilization. The use of morphine also exposes patients to side effects (nausea, vomiting, pruritus, respiratory depression, chronic pain, ileus). Bleeding and hemodynamic risks of peridural and spinal aneshesia limits their use. The postoperative efficacy of deep parasternal intercostal plane block has not yet been evaluated sufficiently. The aim of this study is to evaluate the efficacity of TTMPB on the quality of postoperative recovery after cardiac surgery.

Interventions

PROCEDUREDeep parasternal intercostal plane block

The block is performed bilaterally in the 4th intercostal space. The probe is placed in the latero-median axis and a needle is placed latero-medially between the intercostal and transverse thoracic muscle. The solution is then injected under ultrasound control

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients requiring cardiac surgery with sternotomy

Exclusion criteria

* Emergency procedure * Procedures requiring lateral chest drainage * Hemodynamic instability * Severe kidney or liver failure * BMI \> 40 * Chronic pain * Allergy to local anesthesics * Pregnant woman * Long term opioïds use

Design outcomes

Primary

Measure	Time frame	Description
Quality of recovery 15 (QoR-15)	24 hours after surgery	QoR-15 score : 0 to 150. Addition of 15 items note between 0 to 10 150 = perfect post operative recovery possible 0 = worst post operative recovery possible

Secondary

Measure	Time frame	Description
Total morphine consumption at 24 hours	24 hours after surgery	Total morphine consumption, in milligrams, during the first 24 hours after surgery.

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 8, 2026