Endodontic Treatment, Post Operative Pain Control
Conditions
Keywords
Root canal treatment, Post-operative pain, Corticosteroids, Dexamethasone, Randomised controlled trial
Brief summary
The aim of this research is to assess the effect of intentionally extruding a corticosteroid intracanal solution into the periapical tissues on the postoperative pain after root canal treatment in patients with symptomatic irreversible pulpitis and symptomatic apical periodontitis (SIP/SAP). The main question it aims to answer: Is there an analgesic effect of extruding an intracanal solution of DXA into the periapical tissues in patients diagnosed with SIP/SAP? Researchers will compare dexamethasone to a placebo to see if the extrusion dexamethasone works in reducing post-endodontic treatment pain.
Interventions
OTHERPlacebo
2ml of normal saline will be used as placebo to be flushed and extruded through the canals to the periradicular tissues
DRUGDexamethasone
a 2 ml solution of dexamethasone (3.3mg/ml) will be flushed in the root canal and intentionally extruded to the periradicular tissues to assess its potnetial sedative effect
Sponsors
University of Jordan
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Caregiver)
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* A diagnosis of irreversible pulpits with symptomatic apical periodontitis * Adult patients (aged 18 - 70) * Healthy patients or those with a well-controlled disease (ASA I & II)
Exclusion criteria
* A diagnosis of necrotic pulp, or normal apical tissues * Patients with a severe systemic disease (ASA III or higher) * Patients who received analgesics12 hours before presentation * Previously treated/initiated Endodontics treatment on the same tooth * Unopposed teeth * Third molar teeth * Non-restorable teeth * Periodontally compromised teeth * Pregnant or lactating patients
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Post-operative pain following root canal treatment | at 12, 24, 48 and 72 hours after completing the treatment | The outcome measure is patient-reported pain following root canal treatment. Patients will be given a questionnaire to complete, on 4 different time intervals following the completion of their root canal treatment (12, 24, 48 and 72 h). For each time interval, patients will be asked to fill out: 1. their perceived pain level on a standard 100mm visual-analogue scale, with pain values ranging from zero (no pain at all) and ascending gradually until 100 (worst imagined pain). 2. Whether they needed to take any analgesics. In this case, details about the type, route, dose and timing of the analgesic taken will have to be filled out |
Contacts
Primary ContactRenad H Khanfer
Backup ContactAhmad M El Ma'aita
Outcome results
None listed