Impact of Perioperative Nutritional Status and Management in the Context of Resectable Pancreatic Adenocarcinoma

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06893536

Acronym

PAAD

Enrollment

100

Registered

2025-03-25

Start date

2023-10-12

Completion date

2025-10-12

Last updated

2025-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pancreatic Adenocarcinoma

Keywords

Pancreatic Adenocarcinoma, Digestive tract, Hypercatabolism, Malnutrition,

Brief summary

Patients with pancreatic adenocarcinoma are frequently in a situation of malnutrition, in a context of functional alteration of the digestive tract, and hypercatabolism. As a result, nutritional support is frequently necessary perioperatively, but currently does not follow a specific protocol, and without coordination. It then appears the need to evaluate the prevalence of malnutrition, its impact on perioperative morbidity and mortality, and current management methods. Depending on the findings, subsequent interventional studies will be carried out on the subject, exploring the different modalities of artificial nutrition.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

* Major subject (≥18 years old) * Subject with pancreatic adenocarcinoma authenticated by pathology * Subject candidate for curative surgical treatment * Subject operated on in the visceral and digestive surgery department, NHC Strasbourg, during the period from January 1, 2018 to December 31, 2022 * Absence of written opposition in the subject's medical file to the reuse of their data for scientific research purposes.

Exclusion criteria

* Subject having expressed opposition to participating in the study * Subject presenting a metastatic form or one not accessible to surgical treatment considered curative of pancreatic adenocarcinoma * Subject under guardianship or curatorship * Subje

Design outcomes

Primary

Measure	Time frame	Description
Study of the Severity of Perioperative Malnutrition in Pancreatic Adenocarcinoma	Up to 1 year	The CCI score measures a patient's postoperative outcome based on the number and severity of complications occurring on a scale of 0 to 100: 0: No complications 100: Death

Countries

France

Contacts

Primary ContactZineb CHERKAOUI, MD

zineb.cherkaoui@chru-strasbourg.fr33 3 69 55 13 15

Outcome results