Advanced Adenomas (AA), Colorectal Carcinoma
Conditions
Brief summary
This is a prospective, multicenter, case-control study. The aim is to develop an optimized algorithm by combining the levels of molecular markers in plasma together with risk factors for developing colorectal cancer and clinical data of patients diagnosed with CRC or AA and healthy individuals.
Interventions
None listed
Sponsors
ADVANCED MARKER DISCOVERY S.L.
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Patients over the age of 18 who are able to understand the participant information and sign the informed consent. * Patients who are going to undergo colonoscopy or surgical resection for tumor (CRC).
Exclusion criteria
* Patients who had developed any type of cancer in the 5 years prior to their participation in this study. * Patients who have received previous chemotherapy or radiotherapy. * Patients diagnosed with non-advanced adenomas, serrated polyps, Familial Adenomatous Polyposis or Lynch Syndrome. * Patients with inadequate bowel preparation for colonoscopy. * Patients who have undergone colonoscopy/polipectomy in the previous 5 years. * Patients with hemolyzed plasma.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Clinical Validation | 36 months | To clinically validate the diagnostic capability of the algorithm for early detection of CRC and AA that combines molecular markers and risk factors |
Countries
Spain
Contacts
Primary ContactMarta Jimenez
Outcome results
None listed