Neuropathic Diabetic Ulcer - Foot
Conditions
Keywords
Hyperbaric oxygen therapy, polarized light therapy, neuropathic foot ulcer
Brief summary
Neuropathic ulcers develop due to nerve damage (neuropathy), commonly seen in conditions like diabetes, leading to loss of sensation, repetitive trauma, and poor wound healing. These ulcers typically occur on weight-bearing areas, hyperbaric oxygen and polarized light therapies may have a synergistic effect, improving oxygenation, cellular activity, and overall healing outcomes in neuropathic ulcers, particularly in diabetic foot ulcers.
Interventions
OTHERHyperbaric oxygen therapy combined with polarized light therapy
Optimum regime of therapy increase healing rate of neuropathic foot ulcer is a challenge for researchers to save patient normal life
OTHERtraditional treatment
topical medication
Sponsors
Al-Zaytoonah University of Jordan
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
55 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* All patients had cardiac ejection fraction (CEF) 50% * blood pressure (BP) 150/90mmHg. * Chest X-ray was reported normal * all patients were clinically evaluated by a specialized ear, nose, and throat (ENT) physician to ensure suitability for the hyperbaric chamber.
Exclusion criteria
* chronic obstructive pulmonary disease, malignancy * cardiac pacemakers, or any disorder that lead to ulcers other than diabetes * chronic peripheral arterial disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ulcer volume using Saline injection method | 4 weeks |
Secondary
| Measure | Time frame |
|---|---|
| Tcpo2 at ulcer edge using Pulse Oximeter | 4 weeks |
| Emg pre and at end (Sensory NCS (Sural nerve) | 4 weeks |
Countries
Egypt
Outcome results
None listed