Biomarkers and Unstable Carotid Plaque

EVALUATION OF NEW BIOMARKERS IN THE IDENTIFICATION OF UNSTABLE CAROTID PLAQUE

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06887894

Enrollment

200

Registered

2025-03-20

Start date

2019-09-01

Completion date

2027-12-31

Last updated

2025-03-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carotid Artery Diseases

Brief summary

This prospective study investigated associations between circulating miRNAs and symptomatic and asymptomatic ICAS, carotid plaque morphology and future cardiovascular events.

Interventions

PROCEDURECarotid endarterectomy

Carotid endarterectomy, plaque histological analysis and miRNA expression

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Presence of significant internal carotid artery stenosis referred to carotid artery endarterectomy. * Age\>18 years

Exclusion criteria

* Presence of significant internal carotid artery stenosis referred to carotid artery stenting

Design outcomes

Primary

Measure	Time frame	Description
miRNA levels	30 days	miRNA levels and plaque vulnerability

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026