Laparoscopic Toupet Fundoplication, Radiological Negative, Endoscope, Hiatal Hernia
Conditions
Brief summary
This study aims to assess the feasibility and effectiveness of laparoscopic toupet fundoplication (LTF) for treating gastroesophageal reflux disease (GERD) symptoms and disease-specific Quality of Life (QoL).
Detailed description
Heartburn, regurgitation, dysphagia, and chest pain are regarded as common esophageal symptoms of gastroesophageal reflux disease (GERD). On the other hand, there are very few reports of laryngopharyngeal reflux (LPR), which is associated with persistent upper airway contact, acidic and non-acidic reflux, and aerosol that results in posterior laryngitis, edema, and glottis erythema. Proton-pump inhibitor (PPI) therapy, Laparoscopic Nissen Fundoplication (LNF), and Laparoscopic Toupet Fundoplication (LTF) have been proven to be effective for the treatment of GERD. However, the therapeutic management of patients with hiatal hernia is debated and treatment remains empirical. Previous studies on PPI therapy and LNF had been published with promising but controversial results. Therefore, the role of LTF is even less explored and evidence is scarce
Interventions
PROCEDURELaparoscopic toupet fundoplication
Patients will undergo laparoscopic toupet fundoplication.
Sponsors
Minia University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Age above 18 years old. * Both sexes. * Hiatal hernia patients (Hill's grade III & IV) by endoscopy and negative by radiology indicated for Toupet fundoplication.
Exclusion criteria
* Recurrent patients. * Age above 70 years old * Unfit for surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of recurrence | 1 year postoperatively | Incidence of recurrence will be recorded |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of anatomical failure | 1 year postoperatively | Incidence of anatomical failure will be recorded |
| Incidence of complications | 1 year postoperatively | Incidence of complications such as dysphagia, chest pain on eating, gas-bloat, postprandial fullness, restriction in belching, and increased flatus will be recorded. |
Countries
Egypt
Contacts
Primary ContactAbdelrahman M Salah, MD
Outcome results
None listed