Osteosclerotic Changes on CT Predict Survival in Prostate Cancer

Osteosclerotic Changes on Computed Tomography Predict Disease Progression and Poor Survival in Prostate Cancer

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06883474

Enrollment

211

Registered

2025-03-19

Start date

2010-07-01

Completion date

2023-05-30

Last updated

2025-03-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prostate Cancer (Adenocarcinoma), Prostate Cancer Metastatic Disease

Keywords

Bone metastasis, computed tomography, osteosclerotic change, prostate cancer

Brief summary

The study specifically investigated PC patients with bone metastasis and conducted a comprehensive analysis of the correlation between OCs and patient survival outcomes.

Interventions

OTHEROsteosclerotic Changes on Computed Tomography

Osteosclerotic Changes on Computed Tomography

Sponsors

Sun Yat-sen University

Lead SponsorOTHER

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

MALE

Healthy volunteers

No

Inclusion criteria

* 1）Histopathological confirmation of prostate adenocarcinoma * 2）Radiologically verified bone metastasis, assessed through bone scintigraphy and CT imaging from the initiation of systemic therapy until disease progression.

Exclusion criteria

* 1）Lacking of complete clinical profiles.

Design outcomes

Primary

Measure	Time frame
Radiographic progression-free survival	From enrollment to the end of treatment at 5 years

Secondary

Measure	Time frame
overall survival	From enrollment to the end of treatment at 5 years

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026