the Change in Carotid Intima-media Thickness After Laparoscopic Sleeve Gastrectomy

The Effect of Laparoscopic Sleeve Gastrectomy on the Change in Carotid Intima-media Thickness in Patients With Obesity: Prospective Randomized Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06882616

Enrollment

Registered

2025-03-18

Start date

2024-03-01

Completion date

2025-03-01

Last updated

2025-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carotis Intima-media Thickness, Reduce the Risk of Cardiac Disease, Weight Loss

Keywords

Carotis intima-media thickness, Laparoscopic sleeve gastrectomy

Brief summary

The aim of this study was to compare carotid intima-media thicknesses in laparoscopic sleeve gastrectomy patients preoperatively and at the end of the first postoperative year.

Detailed description

Obesity is not only a disease in itself, but also predisposes to many other diseases. Cardiac diseases are one of the systems that obesity predisposes to. Obesity has been found to increase the risk of cardiac disease by increasing carotid intima-media thickness in patients with obesity. Surgery is known to be the most effective treatment for obesity and laparoscopic sleeve gastrectomy is the most common bariatric surgery procedure. Laparoscopic sleeve gastrectomy may reduce the risk of cardiac disease by reducing carotid intima-media thickness in patients with obesity through effective weight loss.

Interventions

OTHERsurgery

All patients will be perform laparoscopic sleeve gastrectomy. Carotid intima-media thickness will be analyzed preoperatively and at the end of the first postoperative year.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

SCREENING

Masking

NONE

Intervention model description

Prospective, observational

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* 18-65 years old, * BMI \> 35 kg/m2 * Laparoscopic sleeve gastrectomy will be performed * patients with cardiac disease

Exclusion criteria

* patients without cardiac disease * patients who performed other bariatric surgery procedures

Design outcomes

Primary

Measure	Time frame	Description
carotid intima-media thickness	From enrollment to the end of the first year after laparoscopic sleeve gastrectomy	The primary outcome of the study was to compare carotid intima-media thickness at the end of the first postoperative year after laparoscopic sleeve gastrectomy (LSG) with baseline carotid intima-media thickness in patients with obesity. The investigators will measure carotid intima-media thickness with carotid doppler ultrasound before LSG and at the end of the first year after LSG and compare the results.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026