Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Conditions
Keywords
cancer, adolescent, young adult, cognition, memory, exercise, physical activity
Brief summary
This study evaluates relationships among physical activity, thinking, and memory after cancer treatment in survivors of adolescent and young adult cancers.
Interventions
OTHERNon-Interventional Study
Non-Interventional Study
Sponsors
Mayo Clinic
Study design
Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adults (aged 18+ years) * Primary diagnosis of cancer when 15-39 years-old * Access to a desktop computer or laptop with reliable internet access * No gross motor impairments that prohibit ambulation * Willing to complete study requirements * English speaking
Exclusion criteria
* Diagnosed with nonmelanoma skin cancer only * Not diagnosed with cancer in adolescent and young adult (AYA) age range of 15-39 years * Scheduled travel during the study period that is not indicative of individual's normal schedule
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cognitive performance on Stroop task | Up to 4 weeks | Assessed using the CNS Vital Signs computerized testing platform ("brain games"). CNS Vital Signs is a computerized neuropsychological/neurocognitive assessment platform used by clinicians and researchers to objectively evaluate brain function and neurocognitive status, offering a range of tests and tools for assessment and management of various neurological and behavioral conditions. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Cognitive performance on Visual Memory Test | 2 weeks | Assessed using the CNS Vital Signs computerized testing platform ("brain games"). CNS Vital Signs is a computerized neuropsychological/neurocognitive assessment platform used by clinicians and researchers to objectively evaluate brain function and neurocognitive status, offering a range of tests and tools for assessment and management of various neurological and behavioral conditions. |
| Cognitive performance on Verbal Memory Test | 2 weeks | Assessed using the CNS Vital Signs computerized testing platform ("brain games"). CNS Vital Signs is a computerized neuropsychological/neurocognitive assessment platform used by clinicians and researchers to objectively evaluate brain function and neurocognitive status, offering a range of tests and tools for assessment and management of various neurological and behavioral conditions. |
| Cognitive performance on Symbol Digit Coding Test | 2 weeks | Assessed using the CNS Vital Signs computerized testing platform ("brain games"). CNS Vital Signs is a computerized neuropsychological/neurocognitive assessment platform used by clinicians and researchers to objectively evaluate brain function and neurocognitive status, offering a range of tests and tools for assessment and management of various neurological and behavioral conditions. |
| Cognitive performance on Shifting Attention Test | 2 weeks | Assessed using the CNS Vital Signs computerized testing platform ("brain games"). CNS Vital Signs is a computerized neuropsychological/neurocognitive assessment platform used by clinicians and researchers to objectively evaluate brain function and neurocognitive status, offering a range of tests and tools for assessment and management of various neurological and behavioral conditions. |
| Cognitive performance on Continuous Performance Test | Up to 4 weeks | Assessed using the CNS Vital Signs computerized testing platform ("brain games"). |
| Cognitive performance on Reasoning Test | 2 weeks | Assessed using the CNS Vital Signs computerized testing platform ("brain games"). CNS Vital Signs is a computerized neuropsychological/neurocognitive assessment platform used by clinicians and researchers to objectively evaluate brain function and neurocognitive status, offering a range of tests and tools for assessment and management of various neurological and behavioral conditions. |
| Cognitive performance on Four Part Continuous Performance Test | 2 weeks | Assessed using the CNS Vital Signs computerized testing platform ("brain games"). CNS Vital Signs is a computerized neuropsychological/neurocognitive assessment platform used by clinicians and researchers to objectively evaluate brain function and neurocognitive status, offering a range of tests and tools for assessment and management of various neurological and behavioral conditions. |
| Self-reported cognition - FACT-COG | 2 weeks | Evaluated using the Functional Assessment of Cancer Therapy-Cognitive Function (FACT-COG), a 37-item questionnaire assessing cognitive impairment, cognitive abilities, and quality of life over the past 7 days. Responses are on a 5-point scale (Never; About once a week; Two to three times a week; Nearly every day; Several times a day). Higher scores generally indicate better self-reported cognition. |
| Average weekly minutes of physical activity | 2 weeks | Moderate-to-vigorous physical activity (MVPA) will be measured using an accelerometer (activPAL) which participants will wear on their non-dominant thigh for 7 consecutive days. |
Countries
United States
Contacts
CONTACTMelissa Cole
CONTACTClinical Trials Referral Office
PRINCIPAL_INVESTIGATORDiane K. Ehlers, PhD
Mayo Clinic
Outcome results
None listed