Parkinson Disease
Conditions
Brief summary
Parkinson's disease (PD) is a progressive and chronic neurodegenerative disease, which presents signs and symptoms both motor (impaired gait, posture, balance, etc.) and cognitive (memory loss, dementia, etc.), all of which are causing disability and assuming a high economic cost. Currently, there are already certain authors who have shown how a high-intensity interval training (HIIT) protocol produces improvements in cognitive and physical performance in healthy adults6 and in people with multiple sclerosis. However, another modality has been created, such as high-intensity functional training (HIFT), which can benefit different populations, both healthy and pathological, due to the multimodal nature of the exercises. Thanks to multimodality, more aspects such as agility, coordination and precision of movements are worked on compared to unimodal HIIT programs that make this relevant work difficult in a person's daily life. The current study aims to demonstrate the effectiveness of a HIFT training protocol in a specific population, such as people with Parkinson's disease.
Detailed description
The hypothesis is that high-intensity functional training (HIFT), at a motor and cognitive level, provides a greater benefit than conventional programs of strength, balance and cognition, on the functionality and cognitive capacity of people with Parkinson's disease. Overall objective: \- To assess whether the HIFT training program is associated with significant improvements in functional and cognitive capacity compared to conventional strength, balance and cognition programs in Parkinson's patients. Secondary objectives: 1. To assess whether the HIFT program improves the quality of life in patients with PD. 2. To study whether the HIFT program reduces the degree of dependency of patients with PD. 3. To determine if the HIFT program improves physical performance in patients with PD 4. To assess whether the HIFT program reduces the risk of falls in patients with PD. 5. To investigate whether the HIFT program improves balance in patients with PD. 6. To determine if the HIFT program improves functional capacity in patients with PD. 7. To study whether the HIFT program improves cognitive function in patients with PD
Interventions
The pillar of rehabilitation will be based on high intensity functional training. 45-minute sessions divided into 5 minutes of warm-up, 35 minutes of functional exercises, and 5 minutes of going back to bed and cooling down. The 35 minutes of exercises were divided into 3 categories: lower extremity exercises, upper extremity exercises, and static and dynamic coordination and balance exercises. Each category will consist of 3 exercises per session, performing 2-3 series with a maximum of repetitions of 10-RM. The progression of the load will be progressively increased in weeks 3, 5 and 8 between 40-60% of the 1-RM.
Sponsors
Fundacion Para La Investigacion Hospital La Fe
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Intervention model description
Participants will be randomly divided into two groups: experimental group (EG) and control group (CG). The experimental group will perform a HIFT training program and the control group will follow their routine of physical and cognitive exercises, which will be recorded for control purposes.
Eligibility
Sex/Gender
ALL
Age
40 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Diagnosis of Parkinson's disease. * Stage I or II (Hoehn - Yahr Scale). * Age between 45 and 80 years. * Independent ambulation for 10 consecutive minutes. * Regular physical exercise.
Exclusion criteria
* Medical contraindication for physical activity, deafness or limited hearing and very low vision or blind. * Vestibular disorders that compromise balance. * Psychotic or severe cognitive disorder. * Decompensation or changes in medication. * Surgical intervention in the last 6 months. * Sedentary persons
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Trail Making Test A y B | 15 minutes | Evaluation of visual search, scanning, processing speed, mental flexibility and executive functions. |
| Short physical performance battery (SSPB) | 10 minutes | Functional performance evaluation. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Barthel index | 10 minutes | Evaluation of the degree of dependence in activities of daily living. |
| fall risk assessment scale | 5 minutes | Fall Risk Assessment |
| Mini Mental State Examination | 20 minutes | Assessment of cognitive function |
| 2-minute walk test (2-MWT) | 5 minutes | Evaluation of functional capacity |
| SF-12 Health Questionnaire | 10 minutes | Assessing Perceived Quality of Life |
Other
| Measure | Time frame | Description |
|---|---|---|
| The Borg Scale | 2 minutes | Rating of perceived exertion |
Countries
Spain
Contacts
Primary ContactMarta Aguilar Rodríguez, PHD
Outcome results
None listed