Dilated Cardiomyopathy, Ischemic Cardiopathy
Conditions
Brief summary
This project is a pilot study which aims at showing the feasibility of free breathing cardiac MRI using GRICS (Generalized Reconstruction by Inversion of Coupled System)software in a clinical environment. The GRICS technique has been developed by the IADI (Diagnostic, Adaptive and Interventional Imaging)lab, Nancy, France. It enables free breathing MRI thanks to a reconstruction algorithm which provides artefact-free images based on raw MR data and physiological data from external sensors (respiratory belts, ECG. In this study, we want to acquire free breathing cardiac cine images during a standard cardiac MR exam and compare those data with the breath-hold ones.
Interventions
DEVICEAdditional free breathing MR acquisitions
Sponsors
Institut National de la Santé Et de la Recherche Médicale, France
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* candidate to cardiac MR exam because of ischemic or dilated cardiopathy * legally an adult * having heath insurance * having signed the consent form
Exclusion criteria
* dyspnea * atrial fibrillation * pain while lying on the back for a long time * inability to follow a procedure * contraindication to MRI * contraindication to gadolinium chelate injection
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Qualitative image reading by the radiologist | 1 Month | Feasibility of GRICS CardioCine : the radiologist responds to a questionnaire |
| Quantitative image analysis by the radiologist | 1 Month | Feasibility of GRICS CardioCine : the radiologist responds to a questionnaire |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Right ventricular end-diastolic volume | Day 1 | Free-breathing and breath-hold measurements |
| Left ventricular end-diastolic volume | Day 1 | Free-breathing and breath-hold measurements |
| Right ventricular end-systolic volume | Day 1 | Free-breathing and breath-hold measurements |
| Left ventricular end-systolic volume | Day 1 | Free-breathing and breath-hold measurements |
| Right ventricular systolic ejection volume | Day 1 | Free-breathing and breath-hold measurements |
| Left ventricular systolic ejection volume | Day 1 | Free-breathing and breath-hold measurements |
| Right ventricular ejection fractions | Day 1 | Free-breathing and breath-hold measurements |
| Left ventricular ejection fractions | Day 1 | Free-breathing and breath-hold measurements |
| Left ventricular mass in diastole | Day 1 | Free-breathing and breath-hold measurements |
| Aortic flow | Day 1 | Free-breathing and breath-hold measurements |
| Analysis of the segmental kinetics of the left ventricle | Day 1 | Free-breathing and breath-hold measurements |
Countries
France
Outcome results
None listed