Fish Oils
Conditions
Brief summary
The goal of this clinical trial is to test the effect of fish oil supplement in terms of vision in children and adolescents. The main question it aims to answer is: the differences in changes of choroidal thickness, choroidal blood flow, axial length, and visual acuity between the intervention group and the control group Participants will take the fish oil supplement. a baseline examination will be conducted, followed by follow-up visits at 15, 30, and 90 days after the start of the intervention.
Interventions
DIETARY_SUPPLEMENTfish oil
Twice a day, with one dose of DHA 300mg: EPA 60mg, for a continuous intervention of 90 days
Sponsors
Shanghai Eye Disease Prevention and Treatment Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
6 Years to 9 Years
Healthy volunteers
Yes
Inclusion criteria
1. Age range: 6-9 years old, gender unspecified; 2. Equivalent spherical power after unilateral cycloplegic eye ranging from 0.75D to -0.5D, with astigmatism not exceeding 1.5D; 3. Best corrected visual acuity of at least 1.0; 4. Ability to sign an informed consent form with the presence and understanding of a parent or guardian.
Exclusion criteria
1. Allergy or intolerance to ω-3 PUFAs or cycloplegics; 2. Strabismus, history of eye surgery (including strabismus correction surgery), other eye diseases, or systemic diseases; 3. Currently using myopia prevention measures.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Axial length | 15±2 days, 30±2 days, and 90±2 days | the change of axial length |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| change in equivalent spherical | 15±2 days, 30±2 days, and 90±2 days | change in equivalent spherical in both eyes |
Countries
China
Outcome results
None listed