Multicenter Randomised Prospective Study for External Support Mesh VEST of Venous Coronary Grafts on the Right Territory

Multicenter Randomised Prospective Study for External Support Mesh VEST of Venous Coronary Grafts on the Right Territory: Mid-term Clinically Driven Re-rivascularization Events Comparison Between Sites Treated With VEST, Sites Treated With Bare Vein, Sites Treated With Other Conduits and de Novo Lesions on the Native Vessels

Status

Recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06877195

Acronym

RiVEST

Enrollment

300

Registered

2025-03-14

Start date

2025-03-01

Completion date

2028-05-01

Last updated

2025-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic Cardiovascular Disease

Keywords

Coronary Artery Bypass Graft

Brief summary

Multicentre randomised prospective study aimed at verifying medium-term patency of venous grafts on the right coronary artery territory, by clinical and/or instrumental follow-up with particular attention to clinically driven re-revascularisation events regarding the site of new lesions (granularly comparing sites already treated with VEST, sites treated with bare vein, sites treated with other conduits, de novo lesions on the native).

Interventions

PROCEDURECABG

Aortocoronary bypass procedures with venous grafts on right coronary territory

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* combined or isolated interventions * adequate vein calibre * adequate graft flowmetry

Exclusion criteria

* inability to implant due to calibre disparity or inadequate flowmetry

Design outcomes

Primary

Measure	Time frame	Description
Ri-revascularization of grafted territory	Till end of study (at least three years)	Incidence of coronary ri-revascaularization by either angioplasty or surgical bypass concerning the grafted territory due to graft failure

Secondary

Measure	Time frame	Description
Major Cardiovascular and Cerebrovascular Events (MACCE)	Till end of study (at least three years)	Incidence of Major Cardiovascular and Cerebrovascular Events

Countries

Italy

Contacts

Primary ContactLuca Paolo Weltert, MD

lweltert@gmail.com+393478880617

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026