Abdominal Aortic Aneurysms (AAA), Endovascular Aneurysm Repair (EVAR)
Conditions
Keywords
Abdominal Aortic Aneurysms (AAA), Endovascular Aneurysm Repair (EVAR), Single antiplatelet therapy, Dual antiplatelet therapy
Brief summary
This study was a target trial emulation using the National Health Claims database established by the Korean National Health Insurance Service (K-NHIS). 8,325 patients were included.
Detailed description
Among these patients, any patients who were prescribed SAPT or DAPT at the date of discharge from the index hospitalization for standard EVAR were defined as being in the SAPT group (N=4,162) and the DAPT group (N=4,163), respectively.
Interventions
None listed
Sponsors
Samsung Medical Center
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* All patients who underwent EVAR for AAA and were successfully discharged
Exclusion criteria
* Patients who had experienced a myocardial infarction * Patients who had experienced a stroke * Patients who had experienced percutaneous coronary intervention * Patients who had history of peripheral disease * Patients who had major bleeding event within 1 year of admission * Those prescribed non-vitamin K antagonist oral anticoagulant or warfarin * Patients who did not prescribe any antiplatelet therapy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Major adverse cardiac and cerebrovascular events (MACCE) | 1 year after EVAR | composite of all-cause death, myocardial infarction (MI), or ischemic stroke |
| Major or clinically relevant non-major bleeding | 1 year after EVAR | Diagnostic codes in the primary or secondary position and transfusion receipt |
| Re-intervention or surgery for AAAs | 1 year after EVAR | Re-intervention or surgery for AAAs |
Outcome results
None listed