Temporomandibular Joint Disorder
Conditions
Keywords
Temporomandibular disorders, TMD, Cortisol
Brief summary
t is recognized that cortisol, a hormone produced by the adrenal glands, is a marker that is elevated in patients with psychological disorders, particularly anxiety. On the other hand, Temporomandibular Disorders (TMD) are a condition with a multifactorial etiology, in which emotional disturbances play a crucial role. Therefore, the aim of this study is to evaluate whether patients with TMD have higher levels of salivary cortisol compared to the general population. Initially, an assessment will be conducted using the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) protocol to determine whether the patient suffer of any kind of Temporomandibular Disorder. Based on the results, individuals will be classified into two groups: the study group, consisting of patients with TMD, and the control group, composed of individuals without the disorder. Those who agree to participate will be required to sign an informed consent form. Subsequently, a saliva sample will be collected for analysis.
Interventions
None listed
Sponsors
University of Coimbra
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Patients who attend the dental clinic of the Faculty of Medicine of University of Coimbra
Exclusion criteria
* Pregnant women, minors and non-autonomous individuals
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Salivary cortisol concentration | One day | The collection should be performed at the time specified by the physician and at least 30 minutes after the ingestion of solid or liquid foods. A collection tube must be obtained from the laboratory, and the following steps should be followed: Remove the smaller tube from the collection kit. Open the tube, take out the swab, and place it in the mouth. Gently chew the swab for approximately 1 minute or until swallowing the accumulated saliva becomes unavoidable. Return the swab to the smaller tube, ensure it is securely sealed, and then place it inside the larger tube. Immediately freeze the sample. |
Countries
Portugal
Contacts
Primary ContactBruno Macedo, PhD
Outcome results
None listed