Pancreaticoduodenal; Fistula, Perioperative Complication, Surgery Timing
Conditions
Brief summary
With the advancement of surgical techniques and the increase in pancreatic oncologic diseases, the volume of pancreaticoduodenal surgeries has been increasing year by year in our center, and multiple pancreaticoduodenal surgeries are often performed on the day of surgery. This study will compare the effect of pancreaticoduodenal surgery performed at different times on patient prognosis. This study plans to divide the patients into morning group, afternoon group, and night group through the start time of surgery, and this study plans to analyze subgroups such as laparoscopic pancreaticoduodenal surgery. The outcome indicators include perioperative complications such as pancreatic fistula, bleeding, abdominal infection, hospitalization cost, and length of hospital stay. The conclusions drawn from this study will suggest to surgeons whether pancreaticoduodenal surgery performed at different times of the day will have different outcomes for patients and will guide surgeons on the timing of pancreaticoduodenal surgery.
Interventions
None listed
Sponsors
West China Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
1. Patients must be required to sign an informed consent form; 2. Age 18-80 years, male and female; 3. ECOG Physical Status Score (PS Score) 0 or 1. 4. Pancreaticoduodenectomy at our center without contraindications related to the surgery.
Exclusion criteria
1. Pre-existing or concurrent other malignant tumors 2. Severe cardiopulmonary and renal dysfunction. 3. Autoimmune disease or history of immunodeficiency 4. Active infections and infectious diseases requiring systemic therapy. 5. History of psychotropic substance abuse, alcoholism or drug addiction. 6. Failure to meet the inclusion criteria as determined by the investigator.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| perioperative complication | perioperative | pancreatic fistula; postoperative bleeding; abdominal infection; delayed gastric emptying |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Length of hospitalization | perioperative | Length of admission to surgery; length of surgery; length of postoperative stay to discharge |
Other
| Measure | Time frame | Description |
|---|---|---|
| Cost of hospitalization | perioperative | Cost of surgery; cost of postoperative medications; total cost of hospitalization |
Countries
China
Outcome results
None listed