Breast Carcinoma
Conditions
Brief summary
This study is being done to determine if a clinically available MRI sequence called ZTE imaging better visualizes breast biopsy markers made of bone cement compared to the currently used breast biopsy markers made of metal.
Detailed description
PRIMARY OBJECTIVE: I. To demonstrate that clinically available ZTE imaging allows for better visualization of bone cement breast biopsy markers when compared to conventional breast biopsy markers and pulse sequences. OUTLINE: This is an observational study. Participants undergo standard of care MRI breast imaging with conventional or bone cement breast biopsy markers and complete a questionnaire on study.
Interventions
OTHERNon-Interventional Study
Non-interventional study
Sponsors
National Institute for Biomedical Imaging and Bioengineering (NIBIB)
Mayo Clinic
Study design
Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Age of 18 or older
Exclusion criteria
* Cardiac pacemaker * Implanted cardiac defibrillator * Internal pacing wires * Cerebral, carotid, or aortic aneurysmal clips * Cochlear implants * Implanted tissue expanders * Claustrophobia * Cannot lay prone * Pregnant
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Bone cement marker (BCM) images compared to conventional images | Baseline | Will be assessed using zero echo-time (ZTE) and standard breast biopsy pulse sequences. Two radiologists will interpret images, evaluating the pulse sequences and ZTE images for marker conspicuity. Each sequence will receive a score for conspicuity ranging from 0 to 2. A score of 0 indicates 'not seen, 1 'maybe seen,' and 2 'well seen.' |
Countries
United States
Outcome results
None listed