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Management Strategy for Acute Cholecystitis in the Digestive Surgery Department and Geriatric Unit in Subjects Over and Under 75 Years

Evaluation of the Management Strategy for Acute Cholecystitis in the Digestive Surgery Department and Geriatric Intraoperative Unit in Subjects Over and Under 75 Years of Age

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06873295
Acronym
GERBILLE
Enrollment
424
Registered
2025-03-12
Start date
2023-03-22
Completion date
2024-10-22
Last updated
2025-03-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Cholecystitis

Brief summary

The management of these often frail elderly patients, with more comorbidities and declining functional capacities, is more complex and justifies a specific, tailored approach. Age is also associated with an increasing prevalence of gallstones. The disadvantages of cold surgery (longer hospital stay, higher cost, risk of disease recurrence in the interim, difficult surgery with more scar tissue due to repeated inflammation) have to be weighed against the high operative risk in the case of emergency surgery, leading to strict criteria for early cholecystectomy. These criteria are rarely met in geriatric patients, who thus enter a hospital cycle whose impact on morbidity and mortality, as well as on loss of autonomy, has been demonstrated in this population. What's more, the deteriorating general condition of frail elderly patients means that a number of them end up being definitively rejected for surgery, despite an initial strategy of cold cholecystectomy.

Interventions

None listed

Sponsors

Centre Hospitalier Universitaire de Nīmes
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients over 18 years of age. * Diagnosis of acute cholecystitis. * Hospitalization in the digestive surgery department and geriatric perioperative unit of Nîmes University Hospital.

Exclusion criteria

* Patients under 18 years of age. * Opposition of the patient to his inclusion in the study after sending the letter of information and non-opposition.

Design outcomes

Primary

MeasureTime frameDescription
Rate of patients with an initial cold cholecystectomy strategy who did not undergo surgery, died or underwent emergency surgeryUp to 6 months, from date of first collection to date of end of collectionPercentage

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026