Hemodynamics Instability, Arrhythmias Cardiac, Cerebral Oxygenation
Conditions
Keywords
Low-Medium Flow Anesthesia, Hemodynamics, Oxygenation
Brief summary
The study topic investigates the potential advantages of low-flow anesthesia in terms of physiological protection and resource saving.
Detailed description
The study aims to compare the effects of low and normal flow sevoflurane anesthesia on the frontal QRS-T angle and cerebral oxygenation in laparoscopic cholecystectomy surgery. The primary objective was to evaluate the effects of low-flow anesthesia on hemodynamic stability and arrhythmia risk; the secondary objective was to compare the total sevoflurane consumption in both methods.
Interventions
Both groups will be given sevoflurane and one group will be given low current anesthesia and the other group will be given medium flow anesthesia.
DEVICElow- medium flow anesthetic machine
The study aims to compare the effects of low and normal flow sevoflurane anesthesia on the frontal QRS-T angle and cerebral oxygenation in laparoscopic cholecystectomy surgery.
Sponsors
Umraniye Education and Research Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SCREENING
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
17 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* being ASA1-2 status * between the ages of 18-70 * who are planned for laparoscopic cholecystectomy
Exclusion criteria
* Patients who refuse to give informed consent * Pregnant and breastfeeding patients * Morbidly obese patients (Body mass index over 40) * Patients with uncontrolled diabetes mellitus, with serious cardiovascular, pulmonary, renal, hepatic disease, obstructive sleep apnea, with electrolyte imbalance- Those with a history of alcohol or drug abuse, with perioperative hemodynamic instability * Patients using drugs known to prolong myocardial repolarization * inability to increase SPO2 above 95 despite necessary intervention
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the effects of low-flow anesthesia on hemodynamic stability | in 2 months | The primary objective was to detect the adverse effects of low-flow anesthesia on hemodynamic stability and arrhythmia risk |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| the cerebral oxygenation | in 2 months | The primary objective was to detect the adverse effects of low-flow anesthesia on cerebral oxygenation |
Countries
Turkey (Türkiye)
Contacts
Primary Contactsenay goksu, specialist doctor
Outcome results
None listed