Multiple Sclerosis
Conditions
Keywords
artificial intelligence, exercise, multiple sclerosis, physical therapy, strength, telerehabilitation
Brief summary
Multiple sclerosis (MS) is a neurodegenerative disease affecting the central nervous system and is a leading cause of disability in young adults. It often produces strength deficits. Exercise has been shown to improve strength, mobility, and quality of life while reducing fatigue. Telerehabilitation offers a convenient, accessible alternative for MS patients. This study explores the use of an AI-powered application for prescribing and monitoring strength exercises, ensuring continuous feedback and adherence. Methods: Randomized clinical trial. Intervention of 3 weekly strength training ses-sions for 20 weeks, patients in the experimental group used the AI application, while patients in the control group followed the conventional method, paper-based exercises with access to videos.
Interventions
OTHERTelerehabilitation
EG performed using an artificial intelli-gence (AI) application called RehBody, which detects body segments, assists in cor-recting the technique and monitoring the exercise, number of sets and repetitions done, and the adherence percentage
OTHERExercise program
CG participants followed the exercise program and trained at home with images and videos as support.
Sponsors
University of Cadiz
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Masking description
Enter the total number of arms participants might be assigned to over the course of the clinical study.
Intervention model description
A neurology will be diagnosed the Multiple sclerosis .
Eligibility
Sex/Gender
ALL
Age
35 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* Diagnosis of multiple sclerosis according to the McDonald criteria 2017: * Age between 35 and 60 years. * Score on the Expanded Disability Status Scale in Multiple Sclerosis by Kurtzke (EDSS) between 2 and 6 points. * Patients who do not require assistive devices for home mobility. * Patients with no changes in disease-modifying treatment in the last 3 months. * Patients who have understood, completed, and signed the informed consent and the study information sheet.
Exclusion criteria
* Patients who have been regularly performing strength exercises for more than 3 months prior. * Moderate/severe cognitive impairment that may interfere with the understanding and/or execution of the study. * History of alcohol and/or drug abuse. * Presence of a relapse and/or treatment with corticosteroids within the four weeks prior to the start of the study. * Patients with severe comorbidities other than MS that may pose a risk for following the exercise guidelines or for their participation in the study for other reasons.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Maximal Strength | Baseline | Maxi-mal Strength was assessed using an 8-repetition maximum test , in which par-ticipants perform 8 repetitions of squat and bench press as the resistance is gradually increased until a load is determined where only eight repetitions can be performed. The load increment was determined based on the result from the Modified Borg Scale at the end of the exercise, if the Borg rating was greater than 7, the test was completed. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Maximal Strength. | Ten weeks. | Maxi-mal Strength was assessed using an 8-repetition maximum test, in which par-ticipants perform 8 repetitions of squat and bench press as the resistance is gradually increased until a load is determined where only eight repetitions can be performed. The load increment was determined based on the result from the Modified Borg Scale at the end of the exercise, if the Borg rating was greater than 7, the test was completed. |
| Strength endurance. | Baseline | Strength endurance was measured by the maximum number of unilateral knee flexion-extension repetitions performed in 30 seconds |
| Endurance capacity. | Baseline. | Endurance capacity as secondary variable was measured by 6-minutes walking test , where participants covering the maximum distance on a flat surface in 6 minutes. Fatigue was quantified by Modified Fatigue Impact Scale . |
Countries
Spain
Outcome results
None listed