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General Anesthesia Versus Loco-Regional Anesthesia for Transcarotid Trancatheter Aortic Valve Replacement

General Anesthesia Versus Loco-Regional Anesthesia for Transcarotid Trancatheter Aortic Valve Replacement - a Retrospective Cohort Study

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06870734
Acronym
GALATTAVI
Enrollment
44
Registered
2025-03-11
Start date
2025-03-07
Completion date
2026-03-06
Last updated
2025-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aortic Stenosis

Keywords

general anesthesia, cervical block, locoregional anesthesia, TAVR, cardiovascvular intervention

Brief summary

Transcarotid transcatheter aortic valve replacement (Transcarotid TAVR) has been increasingly used as an alternative to the transfemoral approach. The general anesthesia, locoragional anesthesia or local anesthesia are three anesthesia techniques that can be used for transcarotid TAVR. We aim to compare the locoregional approach to gerneral anesthesia.

Interventions

None listed

Sponsors

University Hospital, Caen
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Adult patients who underwent a transcarotid TAVR at the University Hospital of Caen between October 2021 (when the first TAVR was performed under locoregional anesthesia) and December 2024

Exclusion criteria

* Patient's refusal to allow data collection and lack of data regarding the primary endpoint

Design outcomes

Primary

MeasureTime frameDescription
Primary endpoint7 daysComposite endpoint combining mortality and stroke in the first post-operative week

Secondary

MeasureTime frameDescription
Death7 daysDeath occuring during the first week after intervention
Stroke7 daysStroke occuring during the first week after the intervention
1 year mortality1 yearDeath occuring during the first year after intervention
Vasopressive drugs1 dayUse of vasopressive drugs during the intervention
30 day mortality30 daysDeath occuring during the first month after intervention

Other

MeasureTime frameDescription
Pacemaker implantation7 to 30 daysPacemaker implantation during the index hospitalisation

Contacts

Primary ContactRichard DESCAMPS, MD
descamps-r@chu-caen.fr

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026