Chronic Lung Disease, Quality of Life, Respiratory Function Impaired
Conditions
Brief summary
Chronic lung diseases (CLDs) such as asthma, cystic fibrosis, and bronchopulmonary dysplasia significantly impact pediatric patients' respiratory function and overall well-being. Pulmonary rehabilitation (PR) has been shown to improve lung function, exercise tolerance, and quality of life in affected individuals. However, limited research has been conducted on PR implementation in Egypt.
Detailed description
Pulmonary rehabilitation significantly enhances respiratory function, exercise capacity, and quality of life in pediatric patients with CLDs while reducing healthcare utilization. These findings highlight the necessity of integrating structured PR programs into pediatric respiratory care in Egypt.
Interventions
OTHERstandard medical care
standard medical care
OTHERstructured pulmonary rehabilitation
structured pulmonary rehabilitation program including: * Physical Therapy: Breathing exercises, airway clearance techniques, inspiratory muscle training. * Pediatrics & Chest Medicine: Medical supervision, optimization of pharmacological treatment. * Physiology: Monitoring pulmonary function and physiological responses to exercise. * Public Health: Evaluating program feasibility and its impact on healthcare utilization.
Sponsors
Horus University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
6 Years to 16 Years
Healthy volunteers
Yes
Inclusion criteria
* Diagnosed cases of CLDs, stable clinical condition, and ability to participate in rehabilitation.
Exclusion criteria
* Severe comorbidities, recent respiratory infections, or contraindications to physical activity.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Forced Expiratory Volume in One Second | at basline and after 12-weeks of intervention | FEV₁ is the volume of air that a person can forcefully exhale in the first second of a forced breath after taking a deep inhalation. Interpretation of FEV₁: ≥80% of predicted → Normal 60-79% of predicted → Mild obstruction 40-59% of predicted → Moderate obstruction \<40% of predicted → Severe obstruction |
| Forced Vital Capacity | at basline and after 12-weeks of intervention | FVC is the total volume of air that can be forcefully exhaled after taking the deepest possible breath. Normal Values: Typically ≥80% of the predicted value. Obstructive Lung Disease: FVC may be normal or slightly reduced. Restrictive Lung Disease: FVC is significantly reduced due to decreased lung compliance or lung volume. |
| Peak Expiratory Flow Rate | at basline and after 12-weeks of intervention | PEFR is the maximum speed of expiration achieved after full lung inflation. It is measured in liters per minute (L/min). ormal values depend on age, sex, and height: Adult males: 450-700 L/min Adult females: 300-500 L/min Reduced PEFR: Suggests airway obstruction, such as in asthma or COPD. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Hospitalization Frequency | at basline and after 12-weeks of intervention | Hospitalization frequency refers to the number of times a patient is admitted to a hospital due to disease exacerbation, complications, or treatment failure. Number of hospital admissions within a specific time frame (e.g., per year). Length of hospital stay (days per admission). Emergency department visits requiring inpatient care. |
| Medication Dependency | at basline and after 12-weeks of intervention | Medication dependency refers to the extent to which a patient relies on pharmacological treatment to manage symptoms and maintain functional health. Frequency and dosage of medication use. Number of rescue medication uses (e.g., bronchodilators in asthma). Reduction or discontinuation of medication over time. |
| Parental Satisfaction with Treatment | at basline and after 12-weeks of intervention | Parental satisfaction refers to how parents perceive the effectiveness, convenience, and overall impact of their child's treatment plan. Standardized satisfaction surveys (e.g., Likert scale questionnaires). Interviews or focus groups with parents. Feedback on treatment effectiveness, side effects, accessibility, and ease of use. |
Countries
Egypt
Outcome results
None listed