Neurocognitive Disorder, Robotic Assisted Laparoscopic Radical Prostatectomy, Near Infrared Spectroscopy
Conditions
Brief summary
The aim of this study is to evaluate the effects of the steep Trendelenburg position in robotic prostatectomy cases, where anesthesia depth is monitored using BIS and cerebral perfusion is tracked with NIRS, and to determine the incidence of neurocognitive dysfunction using the MoCA test in the postoperative period. Steep Trendelenburg position and CO₂ pneumoperitoneum during robotic radical prostatectomy lead to significant changes in intracranial pressure and cerebral oxygenation, which may contribute to postoperative neurocognitive dysfunction (POCD). Monitoring anesthesia depth with Bispectral Index (BIS) and cerebral perfusion with Near-Infrared Spectroscopy (NIRS) may help detect early neurocognitive changes, and MoCA test assessments will reveal a measurable decline in cognitive function postoperatively.
Interventions
DIAGNOSTIC_TESTMontreal Cognitive Assessment
Preoperative and postoperative MoCA test scores
Sponsors
Ankara City Hospital Bilkent
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
MALE
Age
65 Years to 100 Years
Healthy volunteers
Yes
Inclusion criteria
* Age ≥ 65 years * ASA II-III risk score * Patients scheduled for robotic radical prostatectomy * Patients who voluntarily agree to participate
Exclusion criteria
* Age \< 65 years * History of neurological or psychiatric disorders * Inability to undergo robotic surgery * Conversion to open prostatectomy during surgery * Patients who do not consent to participate
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| MoCA | preoperatively | Preoperative MoCA test scores |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| NIRS | intraoperatively | NIRS values (right & left) |
Countries
Turkey (Türkiye)
Contacts
Primary ContactBetül Güven Aytaç, Assoc.prof.
Outcome results
None listed