Healthy
Conditions
Brief summary
comparison of blood collection tubes and cell-free DNA extraction to evaluate the best possible combination to obtain high quantity and quality cell-free DNA sample for NGS analyses
Interventions
None listed
Sponsors
University Hospital Tuebingen
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* at least 18 years * no serious condition
Exclusion criteria
* younger than 18 years * serious health condition that leads to higher cfDNA content in blood
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| cfDNA quantity | Baseline, at enrollment | we will assess the quantities in ng/µl of cell-free DNA extracted from plasma |
| cfDNA quality | Baseline, at enrollment | we will assess the fragments length in nucleotides using TermoFisher's Tapestation from the extracted plasma cell-free DNA |
Outcome results
None listed