High Intensity Interval Exercise (HIIE), Overweight and Obese Adults
Conditions
Keywords
oxygen consumption, high intensity interval training, substrate oxydation, catecholamines, obesity
Brief summary
Overweight and obesity, particularly increased total and/or abdominal fat mass (FM), are strongly linked to the development of cardiovascular diseases. Managing obesity effectively requires lifestyle and dietary modifications, including increased physical activity. Among the various exercise strategies, Moderate-Intensity Continuous Training (MICT) and High-Intensity Interval Training (HIIT) are widely recommended for reducing FM. Compared to MICT, HIIT is a time-efficient approach, often perceived as more enjoyable, and has been shown to promote greater total and abdominal fat loss in a shorter period. However, the precise mechanisms underlying this enhanced fat loss remain unclear. This study aims to compare the acute effects of two isoenergetic exercise sessions - MICE (Moderate-Intensity Continuous Exercise) and HIIE (High-Intensity Interval Exercise) - on key physiological responses involved in fat mass loss. Specifically, we will assess plasma catecholamine levels during exercise and recovery, as well as oxygen consumption, substrate oxidation, and appetite over the 2-hour post-exercise period in young females with overweight or obesity. By elucidating the role of catecholaminergic stimulation as a potential regulator of fat mass loss, this research could provide valuable insights for optimizing exercise strategies in weight management and metabolic health.
Interventions
OTHERExercise
Two Exercise Modalities: HIIE and MICE
Sponsors
Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques
Universidade Cidade de Sao Paulo
Study design
Allocation
NON_RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Masking description
Data collected on the volunteers will be made anonymous.
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* women with overwieght or obesity (BMI: 25-35 kg/m²)
Exclusion criteria
* contraceptive use * menopause * irregular menstrual cycle * medical contraindications to intense physical activity, * painful joints, * taking ß-blocker
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Oxygen consumption during exercise and the recovery period | Measurement at rest for 20 minutes, then during warm-up for 10 minutes, then during exercise for 20 minutes and finally during 2 hours after the end of the exercise. | Determination of oxygen consumption during exercise and 2 hours after the exercise session (HIIE and MICE). Determination from Metamax (3D Cortex). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Lipid before and after the exercise. | Measurement at rest for 20 minutes and then during 2 hours after the end of the exercise. | Determination of lipid oxidation before and after the exercise. Lipid oxidation is measured from oxygen and carbon dioxide consumption (Metamax 3D Cortex). |
| Carbohydrate before and after the exercise. | Measurement at rest for 20 minutes and then during 2 hours after the end of the exercise. | Determination of carbohydrate oxidation before and after the exercise. Carbohydrate oxidation is measured from oxygen and carbon dioxide consumption (Metamax 3D Cortex). |
| Catecholamines | 5 collections: before exercise started, at the end of exercise (exercise duration is 20-35 minutes), at 30 minutes, 60 minutes and 120 minutes after the end of exercise | Determination of cathecolamines concentration in blood during exercise and 2 hours after the end of the exercise. |
| Energy intakes 24 hours after the exercise | 24 hours post exercise | Evaluation of energy intakes after the exercise session (HIIE vs MICE). Exercise session finish at 11:30 a.m. After that, at home, participants have to complete by themselves a food-record on which they will describe all their meal during 24 hours after the end of the exercise session. It includes their lunch, dinner and their breakfast the next morning. |
Countries
Brazil
Outcome results
None listed