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Prevalence and Pattern of Headache in Pediatric Epilepsy

Prevalence and Pattern of Comorbid Headache in Pediatric Epilepsy Patients Attending Assiut University Children Hospital.

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06868251
Enrollment
60
Registered
2025-03-10
Start date
2025-05-01
Completion date
2026-12-30
Last updated
2025-03-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epilepsy, Headache Disorders

Keywords

epilepsy, headache, pediatric epilepsy

Brief summary

This study aims to determine the prevalence and characteristics of headaches in children with epilepsy, aged 5-18 years. Approximately 60 children will participate at Assiut University Children's Hospital. The research will involve medical history collection, physical and neurological exams, EEG review, and blood tests. The study seeks to improve understanding of the relationship between epilepsy and headaches in children, potentially leading to better treatment strategies. Participation is voluntary, and the risks are minimal.

Detailed description

The primary aim of this observational cross-sectional study is to estimate the prevalence and characterize headaches in pediatric epilepsy patients. Secondary objectives include identifying potential risk factors and triggers associated with headaches in this population and assessing their impact on quality of life. Participant Criteria Inclusion criteria: Children aged 5-18 years with epilepsy Mentally normal and able to describe symptoms Willing to participate in the study Exclusion criteria: Children unable to express symptoms due to mental retardation, psychiatric illness, or verbal disability Children or parents who refuse to participate Methodology Sample Size: 60 patients, calculated using Epi-info version 7 software, based on a previous study showing 45.7% headache prevalence in pediatric epilepsy patients. Data Collection: Detailed medical history, including neurological, cardiovascular, gastrointestinal, endocrine, and musculoskeletal aspects Comprehensive headache history (onset, location, intensity, quality, duration, frequency, associated symptoms) Epilepsy history (age of onset, duration, type, medication, seizure control) General physical examination Neurological examination Investigations: Electroencephalogram (EEG) using Nihon Kohden model 1200 Neuroimaging studies (MRI, CT) if available Complete Blood Count (CBC)

Interventions

None listed

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
5 Years to 18 Years
Healthy volunteers
No

Inclusion criteria

\- pediatric epilepsy patients (5:18 years of age) who are mentally normal and can describe their symptoms. 2/ Acceptance to participate in this study.

Exclusion criteria

\- / Children who can't express their symptoms properly because of mental retardation, psychiatric illness or verbal disability. 2/ Children or Parents who refused to participate in this study.

Design outcomes

Primary

MeasureTime frameDescription
headache prevelance1 monthTo estimate the prevalence and characters of headache in pediatric epileptic patients

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026