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Outcomes of Posterior Urethral Valve Fulguration

Long-term Evaluation of Patients with Fulguration of Posterior Urethral Valve: a Retrospective Cohort Study

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06867263
Enrollment
35
Registered
2025-03-10
Start date
2025-05-01
Completion date
2027-07-01
Last updated
2025-03-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Posterior Urethral Valve

Brief summary

To evaluate the long-term outcome after fulguration of the posterior urethral valve.

Detailed description

Posterior Urethral Valves (PUV) are the most common cause of lower urinary tract obstruction. More severe forms are detected early in pregnancy (mainly type I), while other forms are usually discovered later in childhood when investigating lower urinary tract symptoms. Bladder dysfunction is common and is associated with urinary incontinence in about 55% (0%-72%). Despite the removal of the obstruction by urethral valve ablation, pathological changes in the urinary tract can occur with progressive bladder dysfunction, which can cause deterioration of the upper urinary tract as well. For this reason, all children with PUV require long-term follow-up, always until puberty. In many cases, the life-long current status is uncertain. The current literature lacks research on long-term outcomes.

Interventions

PROCEDUREFulguration

Posterior urethral valve fulguration

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
MALE
Healthy volunteers
No

Inclusion criteria

* Patients with fulguration of PUV since 1 year or more

Exclusion criteria

* Patients with neurogenic bladder or meningocele or spina bifida . Patients with renal parenchymal disease and inflammation not related to posterior urethral valve . Diabetic patients . Parental refusal .

Design outcomes

Primary

MeasureTime frame
The rate of spontaneous voiding with insignificant or absent PMR ( according to equation to age ) after one year from fulguration of the PUV.One year postoperative

Contacts

Primary ContactKeroles Ashraf Soliman Eskaros Dr
Keroles.ashraf99@gmail.com+201061875665

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026