A Comparative Analysis of Preoperative Liver Volumetry in Living Donor Liver Transplantation

Optimizing Accuracy: a Comparative Analysis of Preoperative Liver Volumetry in Living Donor Liver Transplantation from a Surgeon's Perspective

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06865612

Enrollment

109

Registered

2025-03-10

Start date

2011-11-01

Completion date

2025-01-31

Last updated

2025-03-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver Failure, Living Donor Liver Transplantation

Brief summary

Accurate preoperative graft volume assessment is crucial for successful living donor liver transplantation (LDLT). Although manual and automated computed tomography (CT) volume measurement methods using various volumetric tools are widely used, their accuracy remains uncertain. This study aimed to determine the optimal dry weight correction factor for each method to enhance the prediction of actual graft weight (AGW) and compare the accuracy of different methods.

Detailed description

This study is a retrospective diagnostic accuracy study comparing three liver volumetry methods using preoperative donor CT scans in LDLT.

Interventions

None listed

Study design

Observational model

OTHER

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Patients who underwent hepatectomy for living donor liver transplantation performed by the Department of Surgery at Chungnam National University Hospital under the supervision of the principal investigator.

Exclusion criteria

* Patients deemed unsuitable for participation in this clinical study by the investigator.

Design outcomes

Primary

Measure	Time frame	Description
Accuracy of preoperative estimated graft volume (EGV) compared to actual graft weight (AGW)	From preoperative CT scan (1-2 months before transplantation) to intraoperative measurement (day of transplantation)	The accuracy of preoperative donor CT liver volumetry will be assessed by comparing estimated graft volume (EGV) obtained from three methods (automated, semi-automated, manual) with the actual graft weight (AGW) measured intraoperatively. The error ratio between EGV and AGW will be calculated for each method.

Secondary

Measure	Time frame	Description
Determination of the optimal dry weight correction factor for each volumetry method	From preoperative CT scan (1-2 months before transplantation) to intraoperative measurement (day of transplantation)	The study aims to determine the optimal dry weight correction factor by minimizing the discrepancy between EGV and AGW.

Countries

South Korea

Outcome results