Comparison of Three Types of Sutures in Oral Surgery. Study of Bacterial Colonization, Tissue Reaction and Clinical Characteristics: Randomized Clinical Study

Status

Not yet recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06864559

Enrollment

Registered

2025-03-07

Start date

2025-03-01

Completion date

2025-12-01

Last updated

2025-03-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Infection, Oral Surgery, Third Molar Extraction, Wound Healing Complication

Brief summary

Considering the wide variety of surgical sutures currently marketed in the field of Dentistry, it was decided to conduct a study comparing the microbial adhesion and antibacterial activity of three different types of sutures used in Oral Surgery (Silk, non-absorbable polyamide monofilament and non-absorbable expanded polytetrafluoroethylene).

Detailed description

The general or primary objective is: • To compare 3 non-absorbable suture materials used in oral surgery: silk, polyamide monofilament and expanded polytetrafluoroethylene. The specific or secondary objectives are: * To evaluate how each type of suture influences wound healing and the patient's postoperative period. * To study bacterial colonization in each type of suture. * To determine the tissue reaction and clinical characteristics of each suture.

Interventions

OTHERTo Compare 3 different suture materials used in oral surgery

To compare bacterial colonization, tissue reaction and clinical characteristics such as wound healing and patient postoperative outcomes in 3 different suture materials used in oral surgery.

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients with indication for extraction of a third lower molar retained in an unfavorable position that requires a bayonet incision in the surgical procedure. * Age: patients aged 18 years or older. * ASA I patients (Classification of the American Society of Anesthesiology, 1979): healthy patients who tolerate stress well, without systemic pathology, no anxiety and in whom a therapeutic modification is not necessary.

Exclusion criteria

* Pregnant or breastfeeding women. * Smoking patients.

Design outcomes

Primary

Measure	Time frame	Description
Bacterial colonization	7 days.	Microbiological analysis: CFU and qPCR bacterial count.
Level of inflammation	7 days.	The degree of soft tissue inflammation was assessed using Visual Analogue Scale (VAS).

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026