Post Operative Pain
Conditions
Brief summary
Combined femoral and sciatic nerve block provides surgical anesthesia with better cardiorespiratory stability as compared to the spinal anesthesia blockade which has side effects of hypotension, bradycardia, meningitis, post dural puncture headache, hematoma, and neurological deficit
Detailed description
Combined femoral and sciatic nerve block provides surgical anesthesia with better cardiorespiratory stability as compared to the spinal anesthesia blockade which has side effects of hypotension, bradycardia, meningitis, post dural puncture headache, hematoma, and neurological deficit, Adjuvants are those drugs which, when co-administered with local anesthetic agents, may improve the speed of onset and duration of analgesia and counteract disadvantageous effects of local anesthetics. By adding these adjuvants, the dose of local anesthetics like bupivacaine can be reduced, thereby reducing its side effects like myocardial depression, hypotension, bradycardia, heart block, and ventricular arrhythmias. Based on Combination Wisdom, the use of adjuvants to local anesthetics has been promoted a lot .A wide variety of drugs have been used for both neuraxial and peripheral nerve blocks, and the most commonly used drug as adjuvant is the fentanyl . The addition of dexmedetomidine during US-guided combined femoral and sciatic block for below knee surgery was associated with a prolonged duration of analgesia.
Interventions
DRUGdexmedetomidine as adjuvant to bupivacaine
the efficacy of addition of dexmedetomidine as adjuvants to bupivacaine in femorosciatic nerve block
DRUGFentanyl as adjuvant to bupivacaine
the efficacy of addition of fentanyl as adjuvants to bupivacaine in femorosciatic nerve block
Sponsors
Ain Shams University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Patients aged 18-65 years. * American Society of Anesthesiologists (ASA) physical status I-II, * Scheduled for elective surgery below the knee.
Exclusion criteria
* Allergies to used medications. * Coagulopathy. * Septic patients. * Neurological disease. * Respiratory or cardiac disease. * Diabetes mellitus. * Patients' refusal to participate.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Visual analogue score assessment | 6 hours from performing the block | Score range from zero to ten , lower score indicate accepted out come |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The time of first analgesics required | Immediately after the end of the surgery and for 48 hours | analgesics requirements |
Countries
Egypt
Outcome results
None listed