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Knee Extension Deficit Following an Anterior Cruciate Ligament Reconstruction (Extension Loss)

Investigating the Knee Extension Deficit on Knee Strength Recovery Following an Anterior Cruciate Ligament Reconstruction

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06863610
Enrollment
30
Registered
2025-03-07
Start date
2025-03-15
Completion date
2026-09-15
Last updated
2026-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anterior Cruciate Ligament Injuries

Keywords

ACL, reconstruction, knee, extension deficit

Brief summary

Knee extension loss following an anterior cruciate ligament (ACL) reconstruction is believed to play an important role in quadriceps strength recovery. One of the main goals of the rehabilitation following ACL reconstruction is to restore knee extensor muscle strength. Deficits of more than a five-degree extension range of motion (ROM) could lead to delayed knee functionality and anterior knee pain. However, the effect of knee extension deficits in the early postoperative phase of the ACL reconstruction on knee extensor muscle strength recovery and knee functionality is not yet known. This study aimed to investigate the difference between knee extensor muscle strength recovery and knee functionality in patients with ACL repair who had a knee extension ROM deficit (\>5°) in the early postoperative period and those who did not.

Detailed description

Knee range of motion deficits are significant surgical complications following an anterior cruciate ligament (ACL) reconstruction, and despite current advances in surgical techniques, knee range of motion cannot always be regained. Previous studies reported that knee range of motion (ROM) deficits play an important role in knee extensor muscle weakness and knee osteoarthritis. Thus, deficits in knee extension joint motion are more difficult to tolerate than flexion deficits. It has been reported that a five-degree decrease in the extension ROM of the affected knee compared to the healthy side can lead to secondary complications such as difficulty walking and anterior knee pain. However, the effect of knee extension deficits in the early postoperative phase of the ACL reconstruction on knee extensor muscle strength recovery and knee functionality is not yet known. This study aimed to investigate the difference between knee extensor muscle strength recovery and knee functionality in patients with ACL repair who had a knee extension ROM deficit (\>5°) in the early postoperative period and those who did not.

Interventions

OTHERExtension Deficit (>5 degrees)

Patients who had a knee extension ROM deficit of more than 5 degrees will included

OTHERExtension Deficit (<5 degrees)

Patients who had a knee extension ROM deficit of less than 5 degrees will included

Sponsors

Hacettepe University
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
No

Inclusion criteria

* Patients who underwent ACL repair using hamstring tendon autograft * volunteered to participate in the study between the ages of 18-45 * a non-contact injury mechanism * a Tegner Activity Score \>5 before the injury * regularly attended the rehabilitation program after surgery (not missing more than three sessions)

Exclusion criteria

* Patients who underwent ACL repair with patellar tendon autograft or allograft, revision surgery * underwent meniscus and or cartilage repair in addition to ACL repair * a history of previous knee, ankle, or groin injuries * concomitant systemic and/or neurological pathologies * a history of injury to the contralateral lower extremity * do not want to participate in the evaluations that should be done before the study.

Design outcomes

Primary

MeasureTime frameDescription
Quadriceps Muscle Strength RecoveryQudriceps muscle strength will be measured at 4th weeks (isometric), 12 th weeks (isometric and concentric), 6th months (isometric, concentric, and eccentric) following a surgery.Isometric, concentric and eccentric quadriceps muscle strength will be measured using an isokinetic dynamometer (IsoMed®2000 D\&R GmbH, Germany).
Hamstring Muscle Strength RecoveryHamstring muscle strength will be measured at 4th weeks (isometric), 12 th weeks (isometric and concentric), 6th months (isometric, concentric, and eccentric) following a surgery.Isometric, concentric and eccentric hamstring muscle strength will be measured using an isokinetic dynamometer (IsoMed®2000 D\&R GmbH, Germany).

Secondary

MeasureTime frameDescription
The Y Balance Test. Functional Testing 1Assessments will be conducted at 12th weeks and 6th months following a surgeryThe Y Balance Test will be used. Three repetitions will be conducted for each limb, and mean values were recorded in centimeters.
The Vertical Jump Test. Functional Testing 2Assessments will be conducted at 12th weeks and 6th months following a surgeryThe Vertical Jump Test will be used. Three repetitions will be conducted for each limb, and mean values were recorded in centimeters.
The Single Leg Hop Test. Functional Testing 3Assessments will be conducted at 12th weeks and 6th months following a surgeryThe Single Leg Hop Test will be used. Three repetitions will be conducted for each limb, and mean values were recorded in centimeters
The Lysholm score. Patient-reported outcomes measures 1Self-reported recovery will be recorded at 12th weeks and 6th months following a surgeryThe Lysholm score will be used to assess self-reported recovery. The Lysholm score is an eight-item questionnaire that evaluates patients following knee ligament injury. This is scored on a 100-point scale from 0 (worst symptoms) to 100 (best symptoms), with 25 points attributed to pain, 15 to locking, 10 to swelling, 25 to instability,10 to stair climbing and 5 points each to limping, use of a support and squatting.
The International Knee Documentation Committee subjective knee form (IKDC). Patient-reported outcomes measures 2Self-reported recovery will be recorded at 12th weeks and 6th months following a surgeryThe International Knee Documentation Committee subjective knee form (IKDC) will be used to assess self-reported recovery. IKDC subjective knee form contains 18 selected items designed to measure symptoms. Total IKDC score ranges from 0 to 100, with 100 indicating the absence of symptoms and higher levels of knee function.

Countries

Turkey (Türkiye)

Contacts

PRINCIPAL_INVESTIGATORLeyla Eraslan, Ph. D.

Hacettepe University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Sep 17, 2026