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Effect of Albumin Platelet-Rich Fibrin or Leucocyte- Platelet-Rich Fibrin on Immediate Implant

Clinical and Radiographic Evaluation of Xenograft With Albumin Platelet-Rich Fibrin or Leucocyte- Platelet-Rich Fibrin on Immediate Implant Placement in Mandibular Molar Extraction Sites: Randomized Clinical Trial.

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06863051
Enrollment
20
Registered
2025-03-07
Start date
2025-08-20
Completion date
2027-02-10
Last updated
2025-08-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Immediate Implant Placement

Keywords

Implant, PRF, Albumin

Brief summary

The objective of this study will be to compare between Immediate Implant grafted with xenograft and Alb-PRF gel versus xenograft with L-PRF.

Detailed description

The objective of this study will be to compare between xenograft with Alb-PRF gel and xenograft with L-PRF ( L-PRF Block ) in the aspects of : * Peri-implant vertical defect depth. * Crestal bone level. * Bucco-lingual bone width. * Keratinized tissue width

Interventions

PROCEDUREImmediate Implant Placement and Alb-PRF

Immediate Implant Placement in lower molar region, Grafted with Xenograft and Albumin PRF Gel

PROCEDUREImmediate Implant Placement and L-PRF

Immediate Implant Placement in lower molar region, Grafted with Xenograft and L-PRF

Sponsors

Kafrelsheikh University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

1. Inclusion criteria * The presence of non-restorable mandibular molar. * Patient 18-45 years old * Intact buccal and lingual walls * Good oral hygiene. * Prescence of sufficient restorative space. * Jumping gap more than 2 mm. 2.

Exclusion criteria

* Proximity of anatomical structures * Acute localized infection (suppuration at the surgical field) * Patients on chemotherapy or radiotherapy. * Patients who have systemic disorders (diseases) {diabetes mellitus, autoimmune disease, …etc}, * Pregnant patients. * Smoking and Alcohols. * Presence of periapical pathology affecting the neighboring teeth.

Design outcomes

Primary

MeasureTime frameDescription
Vertical peri-implant bone levelImmediate Post-Operative and 6 months after surgerythe distance between implant platform to the most coronal bone-implant contact
Keratinized tissue WidthImmediate Post-Operative and 6 months after surgeryWidth of Keratinized tissue before and after surgery
Crestal bone levelImmediate Post-Operative and 6 months after surgerydistance between implant platform and bone crest

Secondary

MeasureTime frameDescription
Implant StabilityImmediate Post-Operative and 6 months after surgeryby Smart peg
Bucco-lingual bone widthImmediate Post-Operative and 6 months after surgeryit's measured with a line coinciding with implant platform

Countries

Egypt

Contacts

Primary ContactMostafa Mohamed Fayed, Demonstrator of Periodontology
mostafa.mohamed@den.kfs.edu.eg0201004668099

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026