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Impact of Lung Function Prehabilitation to Postoperative Pulmonary Complications

The Impact of Lung Function Prehabilitation to Postoperative Pulmonary Complications on Patient Undergoing Upper Abdominal Surgery Treated in Intensive Care Unit: A Randomized Controlled Trial

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06862076
Enrollment
40
Registered
2025-03-06
Start date
2023-08-01
Completion date
2024-11-12
Last updated
2025-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pulmonary Complications (PPCs)

Keywords

Prehabilitation, Postoperative pulmonary complications, Upper abdominal surgery, Intensive care unit

Brief summary

The aim of this study is to compare the effect of lung function prehabilitation to postoperative pulmonary complications on patient undergoing upper abdominal surgery treated in intensive care unit.

Interventions

PROCEDURELung Function Prehabilitation

Participants assigned to the prehabilitation group received personalized exercise prescriptions, including aerobic training, muscle strengthening, and inspiratory muscle training with a threshold device. The prehabilitation program was conducted at the participants' homes for a minimum duration of two weeks. Adherence was monitored through logbook entries and video call evaluations to ensure correct implementation of the prescribed exercises.

Sponsors

Indonesia University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* adults 18 years or older * scheduled for the upper abdominal surgery under general anesthesia with intraoperative mechanical ventilation * possess adequate cognitive function to comprehend and follow instructions * possess sufficient physical capacity to perform structured prehabilitation exercises * express willingness to participate in the intervention program before surgery

Exclusion criteria

* pregnancy * pre-existing severe pulmonary diseases such as chronic obstructive pulmonary disease (COPD) * planned laparoscopic procedures * history of significant neuromuscular impairment (e.g: stroke) * declined to participate

Design outcomes

Primary

MeasureTime frameDescription
Postoperative pulmonary complicationsPostoperative day 1 and 3Including pulmonary infections, atelectasis, and diaphragmatic dysfunction. Pulmonary infection is assessed using the Clinical Pulmonary Infection Score (CPIS) and with a threshold of \>6, atelectasis using Lung Ultrasound Score (LUS) of ≥1, and diaphragm ultrasound were used to evaluate diaphragm ratio. CPIS and LUS score assessments were conducted on postoperative day 1 and 3 by trained investigators, diaphragm ratio assessment was conducted preoperatively and on postoperative day 1 and 3, all findings were systematically recorded.

Countries

Indonesia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026