Review of the Literature and Serie of Patients Who Underwent Reconstruction After Wide Local Excision of Nail Apparatus for Melanoma

Review of the Literature and Retrospective, Single-centre Study of a Series of Patients Who Underwent Reconstruction After Complete Nail Resection.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06861023

Enrollment

Registered

2025-03-06

Start date

2025-01-15

Completion date

2025-03-25

Last updated

2025-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Melanoma

Brief summary

Melanomas of the nail bed are often diagnosed at the locally advanced stage. The standard treatment was amputation of the finger or toe, but it has now been established that enlarged excision of the nail plate is sufficient under certain conditions. Reconstruction of the nail system can be performed by several techniques. Here, the investigators present a series of patients reconstructed by INTEGRA (dermal matrix) and skin graft

Interventions

OTHERPatients who have undergone extensive nail resection with reconstruction

The investigators studied a population of 10 patients who underwent nail and nail matrix excision surgery as part of the treatment of subungual melanoma, as well as the reconstruction, the investigators opted for. The specific intervention of this study is based on late postoperative questions (after 3 months)

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Inclusion criteria

* Patients who have undergone enlarged resection of the nail apparatus with immediate or delayed reconstruction in the setting of acral melanoma of the fingers or toes.

Exclusion criteria

* Patients who have amputation, opposition of the pateint to the study.

Design outcomes

Primary

Measure	Time frame	Description
Functional and cosmetic patient satisfaction	3 months minimum postoperative	Scores AOFAS (feet)(score ranging from 0, maximum disability, to 90, no disability), Scores QUICK DASH(score ranging from 0, no disability, to 100, maximum disability) and Mayowrist score (hands)(score ranging from 0, maximum disability, to 100, no disability)

Secondary

Measure	Time frame	Description
Post-operative complications	3 months minimum postoperative	Presence or absence of Postoperative complications (inclusion cyst, nail spicule, need for repeat surgery).
Recurrence of the disease	3 months minimum postoperative	Recurrence of the disease.

Countries

France

Contacts

Primary ContactELISE LUPON

lupon.e@chu-nice.fr06 26 30 63 23

Backup ContactLUC CHOUQUET

ettooluc@gmail.com06 42 75 07 14

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026