Steroid-Sensitive Nephrotic Syndrome
Conditions
Brief summary
This study aims to fill the gaps by determining the efficacy of zinc supplementation in maintaining sustained remission in children with steroid sensitive nephrotic syndrome (SSNS).
Detailed description
There is a need to ascertain the efficacy of zinc supplementation in maintaining sustained remission in children with SSNS, thereby lowering the number of relapses and disease morbidity. The findings of this study could pave the way for reasonable evidence about the role of zinc supplementation is sustained remission in children with SSNS.
Interventions
DRUGZinc supplementation plus standard treatment
children were given 5 mg of elemental zinc sulfate as a single daily dose for children less than 4 years of age and 10 mg for children more than 4 years of age for a total duration of 6 months, along with standard therapy.
Sponsors
Muhammad Aamir Latif
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
2 Years to 12 Years
Healthy volunteers
No
Inclusion criteria
* Both genders * Aged 2-12 years * With steroid-sensitive nephrotic syndrome, with frequent relapses
Exclusion criteria
* Children with steroid-resistant nephrotic syndrome * With a history of chronic systemic illness (cardiac, metabolic, malignancy, pulmonary, neurologic, or rheumatologic) * With a history of kidney disease like polycystic kidney disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Sustained remission | 6 months | Efficacy yes if sustained remission was seen after the treatment. |
Countries
Pakistan
Outcome results
None listed