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Muscle Function and Tenderness Differences in Headache Patients

Muscle Function and Tenderness in Migraine, Tension-Type Headache, and Posttraumatic Headache Patients: a Cross-Sectional Study

Status
Enrolling by invitation
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06859463
Enrollment
90
Registered
2025-03-05
Start date
2025-02-28
Completion date
2026-03-01
Last updated
2025-03-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine, Posttraumatic Headache, Tension Headache

Brief summary

This cross-sectional study aims to compare muscle function of the neck, and shoulder and muscle tenderness in three groups of headache patients: migraine, tension-type headache, and posttraumatic headache. The study will evaluate muscle tenderness through the Total Tenderness Score (TTS) and muscle function through maximum voluntary isometric contraction (MVIC) and rate of force development (RFD). Additionally, functional assessments such as the Cranio-Cervical Flexion Test (CCFT) and Ito Test will be performed.

Interventions

DEVICEMuscle function

Functional evaluation First, the patients will fill the Fysisk Aktivitet Questionnaire, the o Klinisk Oral Fysiologi (KU) Questionnaire and the Harvard Trauma Questionnaire. Then, the evaluator will applicate the Total Tenderness Score (TTS) for evaluating their tenderness in different spots of the head and neck regions. The next evaluation comprehends the evaluation of the maximal voluntary isometric contraction (MVIC) for the different neck movements and the rate of force development (RFD) of the shoulder elevation. After this, patients will perform the cranio-cervical flexion test (CCFT), and, finally, the Ito test to evaluate the lumbar endurance.

Sponsors

Danish Headache Center
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

Criteria: Inclusion Criteria: * Aged 18 to 65 years. * Diagnosis of migraine, tension-type headache, or posttraumatic headache, occurring at least 10 days per month. * For tension-type headache patients, maximum of 3 days per month with migraine.

Exclusion criteria

* Pregnancy. * Significant psychiatric comorbidities (e.g., severe depression). * Medication-overuse headache. * Severe osteoarthritis in the neck or shoulder, or cervical disc herniation.

Design outcomes

Primary

MeasureTime frameDescription
Primary Outcome Measure: 1.Rate of Force Development (RFD)1 yearRate of Force Development (RFD) of the shoulder elevation Maximum voluntary isometric contraction performed as fast and hard as possible using a custom dynamometer for the shoulder elevation movement.

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026