Obesity and Obesity-related Medical Conditions
Conditions
Keywords
obesity, hypothyroidism, Depression
Brief summary
Sleeve gastrectomy (SG) continues to be one of the most popular bariatric procedures all over the world. It has been established that obesity is a predisposing factor for several comorbidities, including life-threatening conditions. Many studies have discussed the impact of sleeve gastrectomy on TSH level. But, since most obese patients have some sort of depression, we will try to study the impact of sleeve gastrectomy, depression and hypothyroidism on each other.
Interventions
PROCEDURElaparoscopic sleeve gastrectomy
laparoscopic sleeve gastrectomy is one of the popular bariatric surgeries known for weight reduction
Sponsors
Zagazig University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* obese patients with depression and hypothyroidism controlled by medical treatment candidate for sleeve gastrectomy
Exclusion criteria
* patients less than 18 or above 60 * other psychiatric or medical disorders. * patients not fit for surgery * un controlled patients
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| wound infection | from one day to 2 weeks post-surgery | wound infection will be identified by pus in the drain or in the wound |
| weight | from one day to one year after surgery | weight of the patient will be measured in Kg using weight scale |
| dose of thyroid replacement therapy | monthly from one day to one year post surgery. | the dose of L-thyroxin is monitored in microgrames |
| gasteric leakage | from one day to 1 week post-surgery | leakage after surgery from staple line measured in ml in the drain |
| thyroid function tests | from one day to one year after surgery | TSH,T3,T4 are measured pre and post operative |
| depression | from one day to one year after surgery | depression status is compared pre-operative and post-operative using depression questionnaire (PHQ-9)( patient health questionnaire-9) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| sex | 2 days pre-operative | sex of patient (male or female) will be recorded before surgery |
| BMI ( Body Mass Index) | 2 days before surgery to one year after surgery | BMI is measured by the sum of weight in kg divided by the squared height in meters |
| age | 2 days pre-operative | age will be measured in years |
Countries
Egypt
Outcome results
None listed