Can Tendon Autograft Function As a Meniscal Transplant

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06858943

Acronym

Enrollment

Registered

2025-03-05

Start date

2022-05-01

Completion date

2024-12-31

Last updated

2025-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Meniscectomy

Keywords

Meniscus ; Peroneus longus autograft

Brief summary

Purpose: To evaluate the functional outcomes after using peroneus longus (PL) tendon autograft as meniscal transplantation in patients with knee joint line pain exaggerated with weight bearing following prior total or subtotal meniscectomy.

Detailed description

This research design is a single center prospective study carried out at a tertiary trauma center hospital between May 2022 and December 2022. This research had ethical Committee Approval which was granted by the Ethics Committee of Cairo University (Institutional Review Board (IRB) number N 207-2024). All patients signed an informed consent before joining this study. This study included 25 patients, with previous history of subtotal or total meniscectomy medially or laterally, who underwent meniscus transplantation using PL tendon autograft.

Interventions

PROCEDUREarthroscopic meniscus reconstruction using a tendon autograft

arthroscopic meniscus reconstruction using a tendon autograft

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Intervention model description

case series of 25 patients

Eligibility

Sex/Gender

ALL

Age

22 Years to 40 Years

Healthy volunteers

Inclusion criteria

* Skeletally mature patients with a history of prior subtotal or total (medial or lateral meniscus) meniscectomy. * Post meniscectomy symptoms (medial or lateral knee joint line pain exaggerated with weight bearing).

Exclusion criteria

* Multi-ligamentous knee injuries. * Skeletally immature patients. * Significant osteoarthritic changes on radiographs (Ahlbäck II- V). * Malalignment on full-length radiographs showing increased stress in the involved knee compartment. * Presence of associated ipsilateral ankle joint problem.

Design outcomes

Primary

Measure	Time frame	Description
Lysholm knee score	baseline, 2 years postoperative	functional knee score, minimum is zero, maximum value is 100, a higher score means a better outcome
Knee Injury and Osteoarthritis and Outcome (KOOS) score	baseline, and 2 years postoperative	osteoarthritis knee score, minimum is zero, maximum is 100, higher score means a better outcome

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026