Postoperative Incidence of Atrial Fibrillation Following Cardiac Surgery

Evaluation of Plasmatic Magnesium Levels and Its Association with Atrial Fibrillation After Cardiac Surgery

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06855550

Enrollment

435

Registered

2025-03-04

Start date

2015-05-04

Completion date

2022-12-12

Last updated

2025-03-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial Fibrillation (AF), Cardiac Surgery, Hypomagnesemia

Brief summary

Introduction: Postoperative atrial fibrillation is one of the most frequent complications in cardiac surgery, with an expected incidence of more than 50% following valve surgery. Hypomagnesemia is also likely to be observed in the postoperative period, and several studies have suggested that it could be related to the incidence of postoperative atrial fibrillation. In this study, via a prospective design and adjustment for multiple covariates, the investigators will seek to determine whether plasma magnesium levels are independently associated with the appearance of postoperative atrial fibrillation. Methods: An analytical design involving a concurrent cohort will be carried out in a high-complexity hospital with a cardiovascular focus. Serial postoperative plasma magnesium measurements will be included as independent variables in a logistic regression model to determine their association with atrial fibrillation after adjusting for multiple covariates.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Adults in postoperative cardiac surgery

Exclusion criteria

* Preoperative atrial fibrillation * Without complete information regarding plasmatic magnesium postoperative measurements

Design outcomes

Primary

Measure	Time frame	Description
Postoperative Atrial fibrilation	Measurement was performed first day after surgery up to 30 days postoperatively or discharge (whichever came first)	Defined as irregular QRS without p wave during 30 seconds in a 12 derivations EKG.

Secondary

Measure	Time frame	Description
Mortality	Measurement was performed first day after surgery up to 30 days postoperatively or discharge (whichever came first)	Overall mortality rate.

Countries

Colombia

Outcome results