Digital Breast Tomosynthesis
Conditions
Brief summary
Compare the diagnostic accuracy of tomosynthesis with 2D mammography in cases with suspected BI-RADS 4 or 5 to determine its potential benefit for staging
Detailed description
Digital breast tomosynthesis (DBT) is a promising 3D imaging technique for breast imaging that use in breast cancer detection. it acquires reconstructed volume data , the data is reconstructed secondarily in mammary slices from several radiographs acquired from different angles of view (-15◦ to +15◦ for Fuji). It theoretically improves the sensitivity of detection by enabling enhanced delimitation of the lesion margins, and the specificity by avoiding the problem of glandular superimposition, By separating overlapping breast tissues & it enhances detection of abnormalities located in different planes. DBT has higher breast cancer detection rates and lower recall rates compared with digital mammography (DM). There is also evidence of the diagnostic efficacy of DBT in women with clinical symptoms and women with screen-detected findings who have been recalled for work-up. Consequently, recommendations have been made about the role of DBT in screening asymptomatic women according to their risk levels, in evaluation of symptomatic women, and in work-up of suspicious DM findings. The main objective of this study was to compare tomosynthesis with 2D mammography in cases with suspected BI-RADS 4 or 5 anomalies, to determine its potential benefit for staging.
Interventions
DEVICEdigital breast tomosynthesis and mammography
tomosynthesis is 3D image for the breast mammography is 2D image for the breast
Sponsors
Assiut University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Inclusion criteria
1. BI-RADS 4 OR 5 LESION that pathologically proved to be breast cancer. 2. No history of previous operations 3. No history of chemotherapy or radiotherapy
Exclusion criteria
1. BI-RADS 1 ,2,3 lesions 2. History of previous operation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Recording The breast density in both tomosynthesis and mammography for the main and satellite lesions | baseline | The breast density according to ACR BIRADS in both tomosynthesis and mammography for the main and satellite lesions |
| Recording the type of lesion in both tomosynthesis and mammography for the main and satellite lesions | baseline | the type of lesion (mass , microcalcification , architectural distortion) in both tomosynthesis and mammography for the main and satellite lesions |
| Recording the probability of multifocality or multicentricity in both tomosynthesis and mammography for the main and satellite lesions | baseline | the probability of multifocality or multicentricity in both tomosynthesis and mammography for the main and satellite lesions |
| Recording the location of the tumor within the mammary quadrants and the depth of the tumor in both tomosynthesis and mammography for the main and satellite lesions | baseline | The location of the tumor within the mammary quadrants (upper , lower , outer , inner ) and the depth (anterior-middle-posterior) of the tumor in both tomosynthesis and mammography for the main and satellite lesions |
| Recording the tumor histopathology type for the main and satellite lesions | baseline | Recording the tumor histopathology type (ductal, lobular , in situ , others) for the main and satellite lesions |
Contacts
Primary ContactSilvia Gamal Rasmy
Backup ContactEman Abo Elhamd
Outcome results
None listed