Dermatology
Conditions
Keywords
skin analysis, skin care products
Brief summary
Evaluate the effects of blood peach extract drink and rose apple extract drink on enhancing hemoglobin and iron levels, and improving skin health.
Interventions
DIETARY_SUPPLEMENTPlacebo Drink
Take one bottle of the product every morning on an empty stomach
DIETARY_SUPPLEMENTBlood Peach Extract Drink
Take one bottle of the product every morning on an empty stomach
DIETARY_SUPPLEMENTRose Apple Extract Drink
Take one bottle of the product every morning on an empty stomach
Sponsors
TCI Co., Ltd.
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy adult females aged 20 to 65; * Preferably those with pale complexion or signs of iron deficiency anemia.
Exclusion criteria
* Currently undergoing or having undergone any medical beauty treatments within the past month (including skincare, laser treatments, chemical peel, injections, or cosmetic surgery); * Outdoor workers (exposed to sunlight for more than 5 hours daily); * Pregnant, breastfeeding, or planning to become pregnant during the trial (self-reported); * Individuals with heart, liver, kidney, endocrine, or other significant organic diseases (self-reported); * Individuals who have undergone major surgery (according to medical history); * Long-term medication users; * Individuals with mental health disorders; * Those who are already regularly taking iron supplements; * Faculty or staff members who are currently enrolled in the principal investigator's courses.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the volume of skin wrinkles | Volume change from Baseline skin wrinkles at 8 weeks | IRV full-face skin analyzer was utilized to measure skin wrinkles. Units: arbitrary units |
| the roughness of skin texture | Rating skin roughness from Baseline skin texture at 8 weeks | IRV full-face skin analyzer was utilized to measure skin texture. Units: arbitrary units |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| the change of skin redness | Change from Baseline skin redness at 8 weeks | Colorimeter was utilized to measure skin redness. Units: arbitrary units |
| the change of mean corpuscular hemoglobin concentration (M.C.H.C) level of blood | Change from Baseline M.C.H.C level at 8 weeks | venous blood was sampled to measure M.C.H.C level |
| the change of ferrous level of blood | Change from Baseline ferrous level at 8 weeks | venous blood was sampled to measure ferrous level |
| the change of ferritin level of blood | Change from Baseline ferritin level at 8 weeks | venous blood was sampled to measure ferritin level |
| the change of Total Iron Binding Capacity (TIBC) level of blood | Change from Baseline TIBC level at 8 weeks | venous blood was sampled to measure TIBC level |
| the change of unsaturated iron-binding capacity (UIBC) level of blood | Change from Baseline UIBC level at 8 weeks | venous blood was sampled to measure UIBC level |
| the change of skin elasticity | Change from Baseline skin elasticity at 8 weeks | Cutometer® was utilized to measure skin elasticity. Units: arbitrary units |
| the change of skin collagen density | Change from Baseline skin collagen density at 8 weeks | Dermalab® Combo was utilized to measure skin collagen density. Units: arbitrary units |
| the change of skin pores | Change from Baseline skin pores at 8 weeks | IRV full-face skin analyzer was utilized to measure skin pores. Units: arbitrary units |
| the change of skin tone | Change from Baseline skin tone at 8 weeks | IRV full-face skin analyzer was utilized to measure skin tone. Units: arbitrary units |
| the change of skin hydration | Change from Baseline skin hydration at 8 weeks | Corneometer® was utilized to measure skin hydration. Units: arbitrary units |
| the change of skin melanin/erythema index | Change from Baseline skin melanin/erythema index at 8 weeks | Mexameter® was utilized to measure skin melanin/erythema index. Units: arbitrary units |
| the change of lip redness | Change from Baseline lip redness at 8 weeks | Antera 3D® was utilized to measure lip redness. Units: arbitrary units |
| the change of Red Blood Cells (RBC) Count of blood | Change from Baseline RBC count at 8 weeks | venous blood was sampled to measure RBC count |
| the change of hemoglobin level of blood | Change from Baseline hemoglobin level at 8 weeks | venous blood was sampled to measure hemoglobin level |
| the change of mean corpuscular volume (M.C.V) level of blood | Change from Baseline M.C.V level at 8 weeks | venous blood was sampled to measure M.C.V level |
Other
| Measure | Time frame | Description |
|---|---|---|
| the change of Advanced glycation end products (AGEs) level of blood | change from Baseline AGEs level at 8 weeks | venous blood was sampled to measure AGEs level |
| The change of self-assessment skin and metabolic circulation condition | Change from Baseline skin and metabolic circulation condition at 8 weeks | A self-assessment questionnaire was collected to evaluate skin and metabolic circulation condition. As for the evalutation of skin condition, the higher score the better; As for evaluation of metabolic circulation condition, the higher score the worse. |
| the change of liver function biomarkers (AST, ALT) of blood | change from Baseline liver function biomarkers at 8 weeks | venous blood was sampled to measure liver function biomarkers |
| the change of renal function biomarkers (creatinine, BUN) of blood | change from Baseline renal function biomarkers at 8 weeks | venous blood was sampled to measure renal function biomarkers |
| the change of fasting glucose level of blood | change from Baseline fasting glucose level at 8 weeks | venous blood was sampled to measure fasting glucose level |
Countries
Taiwan
Outcome results
None listed