Regional Distribution Mapping of Lymph Node Metastasis in Epithelial Ovarian Cancer

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06853730

Enrollment

654

Registered

2025-03-03

Start date

2014-01-01

Completion date

2022-12-31

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ovarian Cancer

Keywords

Lymph Node Metastasis

Brief summary

The goal of this observational study is to investigate the metastatic pathways of lymph node involvement in ovarian cancer patients. The main question it aims to answer is: • What are the sequential patterns of lymph node metastasis in ovarian cancer, and are there specific clinical factors associated with different metastatic pathways? Participants diagnosed with ovarian cancer who have undergone lymphadenectomy as part of their standard treatment will have their postoperative pathological lymph node involvement analyzed. The study will retrospectively collect and analyze patient data, including lymph node metastasis patterns, to identify potential progression routes.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Healthy volunteers

Inclusion criteria

i) initial diagnosis and tumor cytoreductive surgery performed at the First Affiliated Hospital of Sun Yat-sen University; ii) confirmed postoperative pathology of epithelial ovarian cancer; iii) available lymph node status; and iv) accessible clinical features, including preoperative ultrasound and blood biochemistry tests

Exclusion criteria

i) initial diagnosis or surgical treatment conducted at other hospitals; ii) absence of imaging results (CT/PET-CT/MRI) or postoperative pathology results for lymph node status. iii) presence of other cancers; and iv) incomplete medical history \-

Design outcomes

Primary

Measure	Time frame	Description
The incidence of lymph node metastasis in ovarian cancer patients and its association with clinical factors.	From enrollment to 6 months post-surgery	The primary goal of this study is to determine the frequency of lymph node metastasis in patients with ovarian cancer and identify clinical factors associated with the occurrence of metastasis.

Outcome results