Socket Preservation Using Dentin Graft Autogenous Dentin Graft With Collagen Sponge on Dental Implant Stability AUTOGENOUS TOOTH GRAFT WITH COLLAGEN SPONGE ON DENTAL IMPLANT STABILITY

Evaluation of Socket Preservation Using Autogenous Dentin Graft With Collagen Sponge on Dental Implant Stability

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06853392

Enrollment

Registered

2025-03-03

Start date

2023-09-15

Completion date

2024-06-01

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bone Loss, Bone Remodeling Disorder, Bone Resorption

Keywords

socket preservation, alveolar ridge defect, Dentin graft, Demineralized freeze dried allograft

Brief summary

The present study was performed to evaluate socket preservation using collagen sponge with autogenous dentin graft versus collagen sponge with de-mineralised freez-dried bone graft on dental implant stability

Detailed description

in our study we made socket preservation using two different grafts in two groups. before grafting we took CBCT we used autogenous dentin graft covered by collagen sponge in one group and demineralized freeze - dried allograft covered with collagen sponge in the other group. after 6 months we Took another CBCT to assist the dimensional changes and bone density in the alveolar socket after grafting We inserted the implant and during insertion we took a core biopsy with trephine bur with external diameter 3 mm for histological analysis. After implant insertion we assisted the stability using RFA.

Interventions

COMBINATION_PRODUCTDemineralized freeze dried allograft with collagen sponge

Demineralized freeze dried allograft,filling 2/3 of the socket covered with collagen sponge ,six months, one time

COMBINATION_PRODUCTautogenous dentin graft with collagen sponge

autogenous mineralized dentin graft, filling 2/3 of the socket covered with collagen sponge , six months, one time

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Intervention model description

test group :socket preservation by dentin graft covered with collagen sponge control group :socket preservation by demineralized freeze dried allograft covered by collagen sponge

Eligibility

Sex/Gender

FEMALE

Age

25 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* Patients are free from any systemic diseases. * Patients with good oral hygiene. * Age range from 25-50 years. * Adequate inter arch space .

Exclusion criteria

* Medications that may affect bone turnover, and bone metabolic diseases. * Smoker patients and alcoholics. * Patients with parafunctional habits. * Patients with active acute infection related to tooth of interest. * Patients with a lack of compliance, and serious mental or psychological problems. * Pregnant females.

Design outcomes

Primary

Measure	Time frame	Description
change in radiographic Socket dimensions from base line to 6 months	6 months following the end of treatment	CBCT measuring socket dimensions
change in bone density from base line to 6 months	6 months following the end of treatment	CBCT measuring bone density within the socket

Secondary

Measure	Time frame	Description
new bone formation	after six months at the time of implant placement	Histological analysis for new bone formation by masson trichrome
implant stability	after six months at the time of implant placement	measuring primary Implant Stability by resonance frequency analysis

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026